Results 101 to 110 of about 7,342,729 (336)

The TRIP database showed most Acute Respiratory Infections questions were already addressed by Cochrane reviews [PDF]

, 2019
OBJECTIVE: Cochrane systematic reviews require more methodological support from Cochrane Review Groups (CRGs) than is customary in journals, CRGs must prioritise reviews to conserve resources.
Brassey, Jon, Carter, Matt, Clark, Justin, Del Mar, Chris, Scott, Anna Mae   +4 more
core   +1 more source

Unique Effect of Aspirin Therapy on Biomarkers in Aspirin-Exacerbated Respiratory Disease: A Prospective Trial.

American Journal of Respiratory and Critical Care Medicine, 2019
RATIONALE Daily high-dose aspirin therapy benefits many patients with aspirin-exacerbated respiratory disease but provides no benefit for aspirin-tolerant asthmatics. Type 2 inflammation characterizes aspirin-exacerbated respiratory disease.
K. Cahill, J. Cui, P. Kothari, Katherine Murphy, B. Raby, Joseph Singer, E. Israel, J. Boyce, T. Laidlaw   +8 more
semanticscholar   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

The Associations of Anaemia Status and Body Mass Index with Asthma Severity in Saudi Arabia: A Comparative Study

Journal of Asthma and Allergy
Alaa A Bugis,1– 3 Bussma Bugis,4 Abdulsalam Alzahrani,1– 3 Ali Hasan Alamri,1– 3 Hamad Hani Almalki,1– 3 Jamal Hassan Alshehri,1– 3 Abdullah Ali Alqarni,1– 3 Faisal A Turkestani1– 3,5 1Respiratory Therapy Program, College of Applied Medical Sciences ...
Bugis AA, Bugis B, Alzahrani A, Alamri AH, Almalki HH, Alshehri JH, Alqarni AA, Turkestani FA   +7 more
doaj  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Level of Awareness About Chronic Obstructive Pulmonary Disease Among Active Smokers

International Journal of COPD
Hajed M Al-Otaibi,1,2 Mazen M Homoud,1,2 Manal M Alqarni,3 Ghadeer J Alsobhi,4 Ghala Zaam Al-Otaibi,2 Nehal A Alnahdi5 1Department of Respiratory Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz University, Jeddah, Saudi Arabia ...
Al-Otaibi HM, Homoud MM, Alqarni MM, Alsobhi GJ, Al-Otaibi GZ, Alnahdi NA   +5 more
doaj  

A high content, phenotypic ‘scar-in-a-jar’ assay for rapid quantification of collagen fibrillogenesis using disease-derived pulmonary fibroblasts

BMC Biomedical Engineering, 2019
Background Excessive extracellular matrix (ECM) deposition is a hallmark feature in fibrosis and tissue remodelling diseases. Typically, mesenchymal cells will produce collagens under standard 2D cell culture conditions, however these do not assemble ...
Robert B. Good, Jessica D. Eley, Elaine Gower, Genevieve Butt, Andrew D. Blanchard, Andrew J. Fisher, Carmel B. Nanthakumar   +6 more
doaj   +1 more source

The Iowa Perinatal Letter, July-August-September 2009, Vol. 30, no. 3 [PDF]

, 2009
This newsletter from The Department of Public Health about perinatal health care and ...

core  

Optimal antimicrobial duration for common bacterial infections [PDF]

, 2019
Most antibiotic use in Australia arises from prescriptions in the community. The risk of antibiotic-related adverse events, including resistance, increases with longer treatment courses.
Daveson, Kathryn, Del Mar, Christopher B., Wilson, Heather L.   +2 more
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source