Tissue resident memory T cells in the respiratory tract
Mucosal Immunology, 2021 Owing to their capacity to rapidly spread across the population, airborne pathogens represent a significant risk to global health. Indeed, several of the past major global pandemics have been instigated by respiratory pathogens.
Ming Z M Zheng, L. Wakim
semanticscholar +1 more source
The incidence and clinical burden of respiratory syncytial virus disease identified through hospital outpatient presentations in Kenyan children [PDF]
, 2012 There is little information that describe the burden of respiratory syncytial virus (RSV) associated disease in the tropical African outpatient setting. Methods We studied a systematic sample of children aged
Ann Bett +35 more
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Elevated microRNA-21 Is a Brake of Inflammation Involved in the Development of Nasal Polyps
Frontiers in Immunology, 2021 BackgroundCRSwNP is an inflammatory disease but the mechanism is not yet fully understood. MiR-21, a member of miRNAs, has been reported to play roles in mediating inflammation.
Ruowu Liu +11 more
doaj +1 more source
Signatures of COVID-19 Severity and Immune Response in the Respiratory Tract Microbiome
medRxiv, 2021 COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection of the respiratory tract, results in highly variable outcomes ranging from minimal illness to death, but the reasons for this are not well understood.
Carter Merenstein +20 more
semanticscholar +1 more source
Serum β2-microglobulin may be a viral biomarker by analyzing children with upper respiratory tract infections and exanthem subitum: a retrospective study [PDF]
PeerJ, 2021 Background Due to the lack of effective and feasible viral biomarkers to distinguish viral infection from bacterial infection, children often receive unnecessary antibiotic treatment.
Xulong Cai +4 more
doaj +2 more sources
An alphaherpesvirus exploits antimicrobial beta-defensins to initiate respiratory tract infection [PDF]
, 2020 beta-Defensins protect the respiratory tract against the myriad of microbial pathogens entering the airways with each breath. However, this potentially hostile environment is known to serve as a portal of entry for herpesviruses.
Boyen, Filip +8 more
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The Diagnostic Value of Metagenomic Next–Generation Sequencing in Lower Respiratory Tract Infection
Frontiers in Cellular and Infection Microbiology, 2021 Lower respiratory tract infections are associated with high morbidity and mortality and significant clinical harm. Due to the limited ability of traditional pathogen detection methods, anti-infective therapy is mostly empirical.
Yan Zheng, X. Qiu, Ting Wang, Jie Zhang
semanticscholar +1 more source
, 2012 Cytological investigation of the pulmonary tract is one of the most useful diagnostic tests available to the clinician. A wide range of samples can be provided to the laboratory from a variety of sampling techniques. In many cases, the cytologist can provide a clear diagnosis of malignancy, infection, or other specific disease.
Michael Sheaff, Naveena Singh
openaire +2 more sources
Zinc and respiratory tract infections: Perspectives for COVID-19 (Review)
International Journal of Molecular Medicine, 2020 In view of the emerging COVID-19 pandemic caused by SARS-CoV-2 virus, the search for potential protective and therapeutic antiviral strategies is of particular and urgent interest.
A. Skalny +11 more
semanticscholar +1 more source