Results 111 to 120 of about 377,838 (168)

Electron compensation‐gated nanomotor for immunomodulation and microenvironment remodeling in bacterial pneumonia therapy

BMEMat, EarlyView.
A nanomotor featuring an “electronic lock” via electron compensation in an Au‐Ag alloy ensures therapeutic precision. Near‐infrared light acts as a key, unlocking on‐demand Ag+ release for synergistic bactericidal action and microenvironment remodeling to potently treat bacterial pneumonia. Abstract Bacterial pneumonia treatment is severely hampered by
Chenglong Xue, Xiaoyu Zhao, Yuqian Wang, Lijin Shi, Qi Shuai   +4 more
wiley   +1 more source

The Value of NLR, PLR, MLR, and SII Combined with Lower Respiratory Tract Symptoms in Predicting Pulmonary Complications in Non-Risk-Factor Influenza A Patients. [PDF]

Int J Gen Med
Ai S, Wu H, Gu R, Zhang S, Luo J, Xu F.
europepmc   +1 more source

Characterization and immunogenicity of nanoparticle vaccines displaying embecovirus spike proteins

Biotechnology Progress, EarlyView.
Virus‐like particle vaccines displaying spike proteins from OC43, HKU1 A, and HKU1 B were evaluated in mice for their ability to elicit antibodies against the spike proteins from OC43, HKU1 A, HKU1 B, and HKU1 C. Abstract Endemic human coronaviruses OC43 and HKU1 cause widespread respiratory infections and can be associated with severe illness in ...
Peter J. Halfmann, Augustine Duffy, Alex Wee, Noah Anderson, Jackson Terrell, Yoshihiro Kawaoka, Ravi S. Kane   +6 more
wiley   +1 more source

Inappropriate Antibiotic Prescribing in Primary Care: A Systematic Review and Implications for Clinical Practice. [PDF]

Cureus
Khanfar BM, Ali R.
europepmc   +1 more source

Association of Hospital Volume With Outcomes of Pulmonary Embolism in the United States

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Pulmonary embolism (PE) remains a leading cause of mortality in the United States. While prior studies show improved outcomes at higher‐volume centers, the understanding of procedural utilization remains limited. Aims Therefore, this study aimed to evaluate the association of hospital PE volume and intervention utilization with ...
Zihan Gao, Troy N. Coaston, Sidney Hinks, Nida Qadir, Obi Emeruwa, Peyman Benharash   +5 more
wiley   +1 more source

Characterization of the Immune Response after Oral Cholera Vaccination (OCV) and Effects of Mycophenolate Mofetil on Priming of this Immune Response—A Randomized, Placebo‐Controlled Trial

Clinical Pharmacology &Therapeutics, EarlyView.
Mycophenolate mofetil (MMF) is an immunosuppressive drug widely used by solid organ transplant recipients. Although it is known that MMF suppresses immune responses, its exact effects on specific vaccinations have not been investigated yet. Mucosal vaccinations are increasingly used, such as a cholera vaccination consisting of two oral immunizations ...
Boukje C. Eveleens Maarse, Aliede E. in 't Veld, Hendrika W. Grievink, Manon A.A. Jansen, Matthijs Moerland   +4 more
wiley   +1 more source

Decoding the complex receptor landscape of enterovirus D68. [PDF]

PLoS Pathog
Zhao M, Zhang L.
europepmc   +1 more source

External Control Arms in Japan: A Systematic Case Analysis of Documented Regulatory Implementation and Uncertainty Management

Clinical Pharmacology &Therapeutics, EarlyView.
External control arms (ECAs) have emerged as important tools to provide benchmark evidence on comparator effectiveness and thereby support regulatory decision making in situations where randomized controlled trials are difficult to conduct. However, how key methodological elements for ECAs are documented and implemented in practice and how residual ...
Suguru Okami, Alexandros Sagkriotis
wiley   +1 more source

Antibiotic prescribing practices and appropriateness of prescriptions in outpatient paediatric acute respiratory tract infections in Viet Nam. [PDF]

JAC Antimicrob Resist
Nguyen-Tran H, Ngo NL, Do NTT, Vu TVD, Pham TN, Ngan TTD, Thai CH, Khuong TV, Le TTB, Duong TH, Olson D, Nguyen N, Van Doorn HR, Lewycka S.   +13 more
europepmc   +1 more source