Results 131 to 140 of about 591,943 (306)

A network biology-based approach to evaluating the effect of environmental contaminants on human interactome and diseases

open access: yes, 2018
Environmental contaminant exposure can pose significant risks to human health. Therefore, evaluating the impact of this exposure is of great importance; however, it is often difficult because both the molecular mechanism of disease and the mode of action
Iida, Midori, Takemoto, Kazuhiro
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Transdermal Delivery of an mRNA‐Liposome Vaccine via Dissolving Microneedle to Preserve Vaccine Activity and Enhance Immune Activation

open access: yesAdvanced Science, EarlyView.
An mRNA‐liposome vaccine via dissolving microneedles (ML‐DMN) enables efficient skin‐targeted delivery while preserving mRNA integrity and allowing sustained antigen expression. Unlike intramuscular (IM) injection, ML‐DMN engages skin‐resident immune cells, activates antigen‐presenting cells (APCs), and induces strong T cell and cytokine responses at ...
Jeehye Nam   +9 more
wiley   +1 more source

Impact of the 10-valent pneumococcal conjugate vaccine on the incidence of respiratory and ENT diseases and antibiotic consumption in children under 5 years of age in Barnaul [PDF]

open access: yesКлиническая микробиология и антимикробная химиотерапия, 2018
Objective. To evaluate epidemiological efficacy of the 10-valent pneumococcal conjugated vaccine (PCV10) as assessed by the number of episodes of respiratory tract and ENT diseases and by the number of antibiotic courses prescribed for those diseases in
Kozyanova Yu.A., Safyanova T.V.
doaj  

Association of Sinusitis and Upper Respiratory Tract Diseases With Incident Rheumatoid Arthritis: A Case-control Study. [PDF]

open access: yesJ Rheumatol, 2022
Kronzer VL   +8 more
europepmc   +1 more source

Determinant Factors of Pneumonia Among Toddlers [PDF]

open access: yes, 2018
Pneumonia still becomes a public health problems that causing pain and death on toddlers. There are many factors which may influence the increase of pneumonia incidence on toddlers, from the aspect of kid individuals and house anvironment such as ...
Dwi Jatmika, Septian Emma   +3 more
core  

Large‐Scale Genomics Reveals Three‐Source Ancestry and Layered Adaptation to High Altitude in Tibetan Chickens

open access: yesAdvanced Science, EarlyView.
Whole‐genome analysis of 1,054 chickens reveals three ancestral sources (NWC, SYA, and SHF) with distinct temporal entry patterns into the Tibetan Plateau. Route‐specific selection scans, calibrated against a demographic null, suggest complementary functional enrichments—vascular homeostasis (NWC), calcium signaling and cardiac adaptation (SYA), and ...
Zongyi Zhao   +7 more
wiley   +1 more source

Follicular Bronchiolitis in a Nigerian Female Child: A Case Report and Review of the Literature

open access: yesCase Reports in Pediatrics, 2016
Small airways diseases are not uncommon in childhood. They account for about 28.4% of hospital admissions for lower respiratory tract infections in South West Nigeria, most of which are due to respiratory syncytial virus (RSV) infection.
Nzechukwu Zimudo Ikeri   +6 more
doaj   +1 more source

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