Results 141 to 150 of about 591,943 (306)
Advanced Science, EarlyView.Simply constructed polyvinylpyrrolidone (PVP) modified palladium nanoparticles (PdP NPs) as cytochrome c oxidase (CcO) and superoxide dismutase (SOD) mimic are promising multifunctional nanoreactors to boost mitochondrial respiration chain function and refine homeostasis via regulation of mitochondrial dynamics and proteostasis sensor UPRmt, which ...
Wenshu Cong +8 more
wiley +1 more source
Respiratory tract diseases and cytokine.
Nihon Naika Gakkai Zasshi, 1995 サイトカインは,リンパ球,マクロファージなどの細胞から産生される免疫反応・炎症を調節・制御する因子である.多種類のサイトカインが発見され,呼吸器疾患においてもサイトカインがその病態に関与する事が明らかとなり,あるいは治療に応用されている.主要サイトカインとしては,インターロイキン(IL-1～IL-10),インターフェロン,コロニー刺激因子(CSF),腫瘍壊死因子(TNF)などが知られている.肺線維症においては線維芽細胞増殖に対し, PDGFとIGF-Iが重要な働きをしている事が知られている.サルコイドーシスにおいては, TNF-α, IL-6, PDGF, GM-CSFが肺局所で増加し,肉芽腫形成に関与していると推測されている.気管支喘息では, IL-5は好酸球を活性化し, IgE産生については ...
openaire +2 more sources
Advanced Science, EarlyView.A snap‐top delivery nanosystem based on an azobenzene metal–organic framework achieves targeted release of 6‐mercaptopurine via acid‐stable frameworks and hypoxia/pH dual‐responsive β‐cyclodextrin gates. This multifunctional platform integrates three synergistic mechanisms: precision drug delivery to inflammatory sites, intrinsic antioxidant properties
Xin Li +6 more
wiley +1 more source
Advanced Science, EarlyView.This study proposes a piezoelectric interface modification strategy to amplify the piezoionic effect. The piezoelectric interface generates an intrinsic electric field, which not only drives rapid ion migration but also concentrates polarized ions on the interface. The flexible sensor delivers superior performance, such as a quick response rate, strong
Yanyu Chen +5 more
wiley +1 more source
Western Pacific Surveillance and ResponseObjective: A response team was deployed to rural Oddar Meanchey Province, Cambodia, in mid-August 2023, immediately after a cluster of patients with acute febrile illness was reported.
Khemrin Pong +6 more
doaj +1 more source
Advanced Science, EarlyView.After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng +9 more
wiley +1 more source
Common respiratory diseases. [PDF]
, 2010 The self-medication phenomenon in upper respiratory tract infections, rhinosinusitis, asthma, and chronic obstructive pulmonary disease are significant and will continue to increase.
Kilgore, David, Najm, Wadie
core
Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles
Advanced Science, EarlyView.Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu +6 more
wiley +1 more source
Annals of Gastroenterological Surgery, EarlyView.This retrospective study identified low preoperative psoas muscle volume, measured by computed tomography, as an independent predictor of postoperative complications in patients undergoing emergency surgery for strangulated small bowel obstruction. Low psoas muscle volume, particularly in older adults, was associated with cardiopulmonary and systemic ...
Takuya Shiraishi +9 more
wiley +1 more source
Mycoplasma pneumonia: Clinical features and management
Lung India, 2010 Mycoplasma pneumonia is a common respiratory pathogen that produces diseases of varied severity ranging from mild upper respiratory tract infection to severe atypical pneumonia.
Kashyap Surender, Sarkar Malay
doaj