Respiratory tract diseases and cytokine.
Nihon Naika Gakkai Zasshi, 1995 サイトカインは,リンパ球,マクロファージなどの細胞から産生される免疫反応・炎症を調節・制御する因子である.多種類のサイトカインが発見され,呼吸器疾患においてもサイトカインがその病態に関与する事が明らかとなり,あるいは治療に応用されている.主要サイトカインとしては,インターロイキン(IL-1～IL-10),インターフェロン,コロニー刺激因子(CSF),腫瘍壊死因子(TNF)などが知られている.肺線維症においては線維芽細胞増殖に対し, PDGFとIGF-Iが重要な働きをしている事が知られている.サルコイドーシスにおいては, TNF-α, IL-6, PDGF, GM-CSFが肺局所で増加し,肉芽腫形成に関与していると推測されている.気管支喘息では, IL-5は好酸球を活性化し, IgE産生については ...
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Linkage of Upper and Lower Respiratory Tract Allergies-a New Concept of One Airway One Disease-
, 2022 Masami Taniguchi
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Advanced Science, EarlyView.Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng +9 more
wiley +1 more source
High quality draft genome sequences of Mycoplasma agassizii strains PS6T and 723 isolated from Gopherus tortoises with upper respiratory tract disease [PDF]
, 2018 David Alvarez‐Ponce +4 more
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Microbial communities of the upper respiratory tract in mild and severe COVID-19 patients: a possible link with the disease course [PDF]
, 2023 Julia S. Galeeva +14 more
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Advanced Science, EarlyView.FPD‐GELNs co‐deliver Su and bioactive components. This active‐passive dual‐targeting strategy suppresses the progression of RCC through the following mechanisms: 1) inhibition of the PI3K‐Akt signaling pathway; 2) downregulation of ABCB1/P‐gp to enhance the chemosensitivity of RCC to Su; and 3) reprogramming of macrophages toward M1 polarization and ...
Haoyu Xu +8 more
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Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy
Advanced Science, EarlyView.Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro +6 more
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Mycoplasma pneumonia: Clinical features and management
Lung India, 2010 Mycoplasma pneumonia is a common respiratory pathogen that produces diseases of varied severity ranging from mild upper respiratory tract infection to severe atypical pneumonia.
Kashyap Surender, Sarkar Malay
doaj
Quality of Antibiotic Prescribing for Respiratory Tract Disease in Primary Healthcare Centers in the District of Tegal, Central Java, Indonesia [PDF]
, 2020 Farida Fakhrunnisa +2 more
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Stromal Cell‐Mast Cell Communication Orchestrates Anti‐Viral Immunity in the Meninges
Advanced Science, EarlyView.This study delineates the spatial distribution and postnatal maturation of meningeal mast cells and uncovers their essential role in antiviral immunity. Using genetic models, mast cells are shown to promote CD8⁺ T cell infiltration and viral clearance via IL‐33 receptor signaling and synergistic activation by IL‐33 and ATP from infected stromal cells ...
Qingqing Li +7 more
wiley +1 more source