Results 131 to 140 of about 834,867 (353)

Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections.

Cochrane Database of Systematic Reviews, 2017
P. Schuetz, Yannick Wirz, Ramon Sager, M. Christ-Crain, D. Stolz, M. Tamm, L. Bouadma, C. Luyt, M. Wolff, J. Chastre, F. Tubach, K. B. Kristoffersen, O. Burkhardt, T. Welte, S. Schroeder, V. Nobre, Long Wei, H. Bucher, N. Bhatnagar, D. Annane, K. Reinhart, A. Branche, P. Damas, M. Nijsten, D. D. de Lange, R. Deliberato, Stella S S Lima, V. Maravić-Stojković, A. Verduri, B. Cao, Y. Shehabi, A. Beishuizen, J. Jensen, C. Corti, J. V. van Oers, A. Falsey, E. D. de Jong, C. F. Oliveira, B. Beghé, M. Briel, B. Mueller   +40 more
semanticscholar   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Genome‐Wide Codon Reprogramming Enables a Multifactorially Attenuated Influenza Vaccine with Broad Cross‐Protection

Advanced Science, EarlyView.
Genome‐wide codon reprogramming of influenza A virus introduces 1956 synonymous mutations across five segments and elevates CpG content, causing defective NA packaging, loss of NS1 accumulation, and enhanced ZAP‐mediated antiviral responses without affecting RNA or protein synthesis. These mechanisms result in profound attenuation and potent homologous
Yang Wang, Tianxin Ma, Yujiao He, Qinming Li, Kailin Mai, Minying Mo, Chenyang Cao, Jiahui Li, Pei Feng, Jiaojiao Peng, Jing Sun, Weiqi Pan, Zifeng Yang, Ling Chen   +13 more
wiley   +1 more source

Duration of frequent or severe respiratory tract infection in adults before diagnosis of IgG subclass deficiency

, 2019
James C. Barton, J. Clayborn Barton, Luigi F. Bertoli   +2 more
openalex   +1 more source

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

Advanced Science, EarlyView.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang, Yi Liu, Zhiying Yao, Haolong Lai, Xiaoxin Chen, Ziqiu Wang, Yiqiong Bao, Tingting Li, Xiaoming Zhou, Xiabin Chen, Peiguo Yang   +10 more
wiley   +1 more source

Reassessment of a meta-analysis of procalcitonin-guided antibiotic therapy for lower respiratory tract infections [PDF]

, 2018
Aarati Keshary, Robert G. Badgett
openalex   +1 more source

Sulfate‐Directed Silver Dendrites with Enhanced Stability for Ultrasensitive SERS‐Based Therapeutic Drug Monitoring

Advanced Science, EarlyView.
This study presents sulfate‐directed silver dendrites (s‐AgDs) as oxidation‐resistant SERS substrates with long‐term stability, reproducibility, and sub‐picomolar sensitivity. Sulfate ions guide anisotropic growth and protect the surface, enabling improved performance over 7 months under ambient conditions.
Aradhana Dwivedi, Jan Dellith, Anna Makarova, Samir F. El‐Mashtoly, Juergen Popp, Vladimir Sivakov, Dana Cialla‐May   +6 more
wiley   +1 more source

Research progress on microecology and childhood respiratory infections via the lung-gut axis

Frontiers in Pediatrics
Respiratory tract infections (RTIs) are a complex global public health challenge, with children being the most affected population. Affected children often exhibit gut microbiota-related symptoms, such as dysbiosis, feeding difficulties, and ...
Zhixuan He, Zixuan Wang, Jiao Yin, Qiang Wang   +3 more
doaj   +1 more source

Impact of temperature relative humidity and absolute humidity on the incidence of hospitalizations for lower respiratory tract infections due to influenza, rhinovirus, and respiratory syncytial virus: results from Community-Acquired Pneumonia Organization (CAPO) International Cohort Study.

, 2017
Timothy L. Wiemken, William A. Mattingly, Stephen Furmanek, Brian E. Guinn, Connor English, Ruth Carrico, Paula Peyrani, Julio A. Ramírez   +7 more
openalex   +1 more source

2224. Reducing Antibiotic Overuse in Adult Lower Respiratory Tract Infections Using Novel Host–Response-Based Diagnostics [PDF]

, 2019
Liran Shani, Salim Halabi, Shachaf Shiber, Meital Paz, Einat Moscoviz, Ami Neuberger, Neta Petersiel, Mordechai Grupper, Dani Kirshner, Daniel A. Haber, Gali Kronenfeld, Niv Mastboim, Tanya Gottlieb, Michal Stein, Nurit Rudich, Naama Sitry, Claire S Guetta, Ester Pri-Or, Ynon Lishtzinsky, Shirly Yanai, ‪Yasmin Maor‬‏, Kfir Oved, Eran Eden, Michael J. Drescher, Mical Paul   +24 more
openalex   +1 more source