Results 131 to 140 of about 896,668 (406)
Molecular pathology of emerging coronavirus infections [PDF]
, 2014 Respiratory viruses can cause a wide spectrum of pulmonary diseases, ranging from mild, upper respiratory tract infections to severe and life-threatening lower respiratory tract infections, including the development of acute lung injury (ALI) and acute ...
Lisa E Gralinski, Ralph S Baric
core +2 more sources
Viral-Bacterial Co-infections in the Cystic Fibrosis Respiratory Tract
Frontiers in Immunology, 2018 A majority of the morbidity and mortality associated with the genetic disease Cystic Fibrosis (CF) is due to lung disease resulting from chronic respiratory infections. The CF airways become chronically colonized with bacteria in childhood, and over time
M. Kiedrowski, J. Bomberger
semanticscholar +1 more source
Advanced Science, EarlyView.This study uncovers that CD38high monocytes discriminate sepsis and sterile inflammation and are associated with 28‐day mortality in bacterial sepsis. Targeting CD38 therapy reduces inflammatory response in monocytes and in sepsis mice model. Mechanistically, CD38‐HIF‐1α/glycolysis/MGO loop exacerbates sepsis‐induced immune dysregulation.
Ning Hua +19 more
wiley +1 more source
The etiology of lower respiratory tract infections in people with diabetes.
Pneumonologia i Alergologia Polska, 2015 Patients with diabetes mellitus (DM) are likely to develop many types of infections, which affect the transport of glucose into tissues. Diabetes increases the susceptibility to different kinds of respiratory infections, is often identified as an ...
Renata Klekotka +2 more
semanticscholar +1 more source
FABP4 as a Mediator of Lipid Metabolism and Pregnant Uterine Dysfunction in Obesity
Advanced Science, EarlyView.Obesity during late pregnancy contributes to uterine smooth muscle dysfunction, but the underlying mechanisms are unclear. This study identifies fatty acid binding protein 4 (FABP4) as a key player in the process, mediating excessive fatty acid uptake, lipid accumulation, and mitochondrial dysfunction in myometrial cells. FABP4 could be a novel uterine
Xuan Li +11 more
wiley +1 more source
BioFactors, Volume 48, Issue 6, Page 1226-1249, November/December 2022., 2022 Abstract Ocular allergies are becoming more prevalent as more airborne pollutants, irritants and microbes pervade our environment. Inflammatory and allergic mediators released by dendritic and mast cells within the conjunctiva cause allergic conjunctivitis (AC), a prevalent ocular surface disorder that affects >40% of the world's human population on a ...
Najam A. Sharif
wiley +1 more source
Potential for Nirsevimab use in Pakistan
Journal of the Pakistan Medical AssociationRespiratory Tract Infections can be classified as upper and lower tract infections. Upper tract infections are more common such as laryngitis and pharyngitis, but the infections of lower respiratory tract are more fatal such as influenza or bronchitis ...
Muhammad Moaz, Basum Hayat
doaj +1 more source
Respiratory Viral Infection-Induced Microbiome Alterations and Secondary Bacterial Pneumonia
Frontiers in Immunology, 2018 Influenza and other respiratory viral infections are the most common type of acute respiratory infection. Viral infections predispose patients to secondary bacterial infections, which often have a more severe clinical course.
Shigeo Hanada +7 more
doaj +1 more source
Acute Respiratory Tract Infections and How to Treat Them [PDF]
, 2019 Acute respiratory tract infections (ARTIs) are one of the most common clinical encounters in primary care settings and they often lead to antibiotic prescriptions. However, more than 90% of ARTIs are caused by viral syndromes.
Seth, Shivani
core +1 more source
Antimicrobial Agents and Chemotherapy, 2015 The Centers for Disease Control and Prevention has promoted the appropriate use of antibiotics since 1995 when it initiated the National Campaign for Appropriate Antibiotic Use in the Community.
Jennifer L Schroeck +5 more
semanticscholar +1 more source