Results 131 to 140 of about 346,658 (267)

Multimorbidity patterns and hospitalizations due to lower respiratory tract infections: a 15-year population-based cohort study. [PDF]

Age Ageing
Franza L, Gentili S, Gregorio C, Beridze G, Marengoni A, Maggi S, Calderón-Larrañaga A, Vetrano DL.   +7 more
europepmc   +1 more source

The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle

ESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.
Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley   +1 more source

Chest Radiography Use in Hospitalized Children with Acute Respiratory Tract Infections: A Baseline Analysis for Imaging Optimization. [PDF]

Children (Basel)
Axinte R, Axinte S, Tătăranu E, Ion L, Frenți AM, Filip F, Burțilă G, Anchidin-Norocel L, Diaconescu S.   +8 more
europepmc   +1 more source

Considerations for drug trials in hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant, Matthias Schmitt, Anna B. Reid, Clifford J. Garratt, William G. Newman, Aneil Malhotra, Rhys Beynon, Masliza Mahmod, Betty Raman, Robert M. Cooper, Dana Dawson, Thomas Green, Sanjay K. Prasad, Anvesha Singh, Susanna Dodd, Hugh Watkins, Stefan Neubauer, Christopher A. Miller   +17 more
wiley   +1 more source

Caregivers' motivations for using pediatric Tuina for recurrent respiratory tract infections in young children in Southern China: a qualitative study. [PDF]

BMC Complement Med Ther
Yin L, Lin M, Chang B, Wu D, Stålsby Lundborg C, Alvesson HM.   +5 more
europepmc   +1 more source

Trends and inequalities in acute respiratory tract infections in Indonesia: an application of the World Health Organization's Health Equity Assessment Toolkit. [PDF]

Trop Med Health
Adnani QES, Adeleye K, Giri B, Osborne A, Aboagye RG, Ahinkorah BO.   +5 more
europepmc   +1 more source

Soticlestat as an adjunctive therapy in children and young adults with Dravet syndrome

Epilepsia, EarlyView.
Overview of the phase 3 trial evaluating soticlestat as adjunctive therapy in children and young adults with Dravet syndrome. Abstract Objective This study evaluated the efficacy, safety, and tolerability of soticlestat as adjunctive therapy in children and young adults with Dravet syndrome (DS).
Joseph Sullivan, Kette Valente, Vicente Villanueva, Adam Strzelczyk, Rima Nabbout, Eiji Nakagawa, Yuehua Zhang, Marta Zolnowska, Yasir Khan, Cheng Dong, Samuel Hsiao, Sarah I. Sheikh, Philipp von Rosenstiel, Mahnaz Asgharnejad, Venkatesha Murthy   +14 more
wiley   +1 more source

Surveillance of epidemiological characteristics and temporal trends in antimicrobial resistance of Haemophilus influenzae in pediatric lower respiratory tract infections (2021-2024). [PDF]

Sci Rep
Li W, Bai Y, Yang C, Sun J, Lu S, Zhao Z.   +5 more
europepmc   +1 more source

An n‐of‐1 gene‐directed drug repurposing trial for an ultrarare genetic condition

Epilepsia, EarlyView.
Abstract Objective Gain‐of‐function (GoF) variants in the KCNC1 potassium channel subunit gene (Kv3.1) cause motor/cognitive delays and hypotonia and have been associated with seizures. Fluoxetine has inhibitory effects on Kv3.1. However, open‐label nonrandomized administration is insufficient to guide clinical decision‐making in ultrarare conditions ...
Vedika Jha, Christina Tsetsos, Mark Bedford, Gregory Costain, Sunita Vohra, Juan Pablo Diaz Martinez, Elise Heon, Jacob Vorstman, Carolina Gorodetsky, Ajoy Vincent, Jesiqua Rapley, Lori Anderson, Evdokia Anagnostou, Danielle A. Baribeau   +13 more
wiley   +1 more source

Acute Respiratory Tract Infections and Severe Disease Among Hospitalized Children.

JAMA Netw Open
Mtaweh H, Kaziev CL, Feinstein CA, Seaton C, Farrar DS, Datta RR, Mahant S, Campigotto A, Freire G, Yeung RSM, Bone JN, Buchanan F, Morris SK, Gill PJ, READAPT-Kids Study Group.   +14 more
europepmc   +1 more source