Results 141 to 150 of about 834,867 (353)

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

T-Cell Profiles In Bronchoalveolar Lavage (BAL) Of Wheezing Children With and Without A History Of Respiratory Syncytial Virus (RSV) Lower Respiratory Tract Infection [PDF]

, 2014
Chang-Kuen Kim, Jin-Tack Kim, Sally E. Wenzel, Marzena Krawiec   +3 more
openalex   +1 more source

Mortality, morbidity, and hospitalisations due to influenza lower respiratory tract infections, 2017: an analysis for the Global Burden of Disease Study 2017

The Lancet Respiratory Medicine, 2019
C. Troeger, B. Blacker, I. Khalil, Stephanie R M Zimsen, Samuel B. Albertson, D. Abate, Jemal Abdela, Tara Ballav Adhikari, S. Aghayan, S. Agrawal, A. Ahmadi, Amani Nidhal Aichour, Ibtihel Aichour, Miloud Taki Eddine Aichour, A. Al-Eyadhy, R. Al-Raddadi, Fares Alahdab, K. Alene, S. Aljunid, N. Alvis-Guzmán, N. Anber, Mina Anjomshoa, C. Antonio, O. Aremu, Hagos T. Atalay, S. Atique, E. Attia, Euripide Avokpaho, A. Awasthi, A. Babazadeh, H. Badali, A. Badawi, J. Banoub, A. Barać, Q. Bassat, Neeraj Bedi, A. Belachew, D. Bennett, Krittika Bhattacharyya, Z. Bhutta, Ali Bijani, F. Carvalho, C. Castañeda-Orjuela, D. Christopher, L. Dandona, R. Dandona, Anh Kim Dang, A. Daryani, M. G. Degefa, F. M. Demeke, M. Dhimal, S. Djalalinia, D. Doku, M. Dubey, E. Dubljanin, Eyasu Ejeta Duken, Dumessa Edessa, M. El Sayed Zaki, H. Fakhim, E. Fernandes, F. Fischer, L. Flor, Kyle Foreman, Teklu Gebrehiwo Gebremichael, D. Geremew, K. Ghadiri, A. Goulart, Jingwen Guo, G. H. Ha, G. B. Hailu, Arvin Haj-Mirzaian, A. Haj-Mirzaian, S. Hamidi, H. Y. Hassen, C. L. Hoang, N. Horita, M. Hostiuc, S. Irvani, Ravi Prakash Jha, J. Jonas, Amaha Kahsay, A. Karch, A. Kasaeian, T. Kassa, A. Kefale, Y. Khader, E. Khan, G. Khan, Md Nuruzzaman Khan, Y. Khang, A. Khoja, J. Khubchandani, R. Kimokoti, A. Kisa, L. Knibbs, S. Kochhar, S. Kosen, P. Koul, A. Koyanagi, Barthelemy Kuate Defo, G. Kumar, D. Lal, Prabhat Lamichhane, C. T. Leshargie, M. Levi, Shanshan Li, Erlyn K Macarayan, M. Majdan, Varshil Mehta, Addisu Melese, Z. Memish, D. T. Mengistu, T. Meretoja, T. Meštrović, Bartosz Miazgowski, G. Milne, B. Milošević, E. Mirrakhimov, B. Moazen, K. Mohammad, S. Mohammed, L. Monasta, L. Morawska, Seyyed Meysam Mousavi, O. Muhammed, S. Murthy, G. Mustafa, A. Naheed, H. Nguyen, N. B. Nguyen, S. H. Nguyen, T. H. Nguyen, M. I. Nisar, M. Nixon, F. Ogbo, A. Olagunju, T. Olagunju, Eyal Oren, J. Ortiz, M. P A, S. Pakhalé, Shanti Patel, Deepak Paudel, D. Pigott, M. Postma, M. Qorbani, Anwar Rafay, A. Rafiei, V. Rahimi-Movaghar, R. Rai, M. S. Rezai, Nicholas Roberts, L. Ronfani, S. Rubino, Saeed Safari, S. Safiri, Z. Saleem, E. Sambala, A. Samy, M. Šantrić Milićević, B. Sartorius, S. Sarvi, M. Savic, M. Sawhney, S. Saxena, S. Seyedmousavi, M. Shaikh, M. Sharif, A. Sheikh, M. Shigematsu, David L. Smith, R. Somayaji, J. Soriano, C. Sreeramareddy, M. Sufiyan, M. Temsah, B. Tessema, Mebrahtu Teweldemedhin, M. Tortajada-Girbés, B. Tran, Khanh B. Tran, Afewerki Gebremeskel Tsadik, K. Ukwaja, I. Ullah, T. Vasankari, G. Vu, Fiseha Wadilo Wada, Yasir Waheed, T. West, C. Wiysonge, Ebrahim M. Yimer, N. Yonemoto, Z. Zaidi, T. Vos, Stephen S. Lim, C. Murray, A. Mokdad, Simon Iain Hay, R. Reiner   +198 more
semanticscholar   +1 more source

Leucine‐Dependent SLC7A5–PGAM5 Interaction Promotes Advanced Atherosclerosis Through Hindering Mitochondrial Function of Macrophages

Advanced Science, EarlyView.
Higher plasma leucine is associated with increased risk of new‐onset myocardial infarction. Leucine deprivation alleviates advanced atherosclerosis in mice. Tumor‐induced leucine deprivation reprograms macrophage metabolism and increases CD5Lhi macrophages in mouse plaques. Mechanistically, leucine deficiency reduced SLC7A5‐PGAM5 binding in macrophages,
Shan Zhong, Xueyu Wang, Qingsong Li, Siqi Wang, Bin Sun, Wenjun Ni, Gengyu Zhou, Fan Wang, Xianwei Xie, Cheng Jin, Gang Xu, Peng Zhao, Xiang Peng, Feiyuan Han, Xiangwen Xi, Yidan Wang, Juan Xu, Yue Wang, Xia Gu, Shuo Li, Jian Zhang, Shuijie Li, Jinwei Tian   +22 more
wiley   +1 more source

The Use of PCR for Respiratory Virus Detection on the Diagnosis and Treatment Decision of Respiratory Tract Infections in Iraq

, 2022
Hany Akeel Al-Hussaniy, Raghid R. Altalebi, Ali Hikmat Alburghaif, Abdul-Ghaffar A. Abdul-Amir   +3 more
openalex   +2 more sources

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

Advanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Yen‐Liang Liu, Gideon Meyerowitz‐Katz, Tsung‐Hsun Tsai, Pen‐Hua Su   +7 more
wiley   +1 more source

Nanozymes Integrated Biochips Toward Smart Detection System

Advanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong, Lingqian Chang   +10 more
wiley   +1 more source

[Respiratory tract infections].

Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2003
Takeshi, Fujii, Shigeru, Kono
  +6 more sources

Epidemiological pattern of community-acquired respiratory tract infections of the conscripts in the North Fleet during a vaccine-challenged period

, 2014
Yu. V. Lobzin, В. В. Рыбаченко, В. М. Мануйлов, Gertraud Mazur   +3 more
openalex   +2 more sources

Artificial Intelligence‐Driven Soft Bioelectronics for Self‐Powered Respiration Monitoring

Advanced Science, EarlyView.
Artificial intelligence‐driven soft bioelectronics for self powered respiration monitoring based on triboelectric nanogenerators (TENGs), piezoelectric nanogenerators (PENGs), and magnetoelastic generators (MEGs) enable continuous and multi‐scenario respiratory biomechanical data collection. Coupled with machine learning and big data driven diagnostics,
Xinkai Xu, Xiao Xiao, Rui Guo, Jun Chen
wiley   +1 more source