Results 41 to 50 of about 834,867 (353)

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

ACUTE RESPIRATORY TRACT INFECTIONS: WIDENING OF POSSIBILITIES OF ANTIVIRAL TREATMENT

Вопросы современной педиатрии, 2013
Problem of effective and safe treatment and prophylaxis of acute respiratory tract infections is one of the most topical problems in clinical pediatrics.
V. A. Bulgakova
doaj   +1 more source

Impact of Stress‐Induced Hyperglycemia on In‐Hospital Medical Complications in Patients With Acute Stroke: From a Large‐Scale Nationwide Longitudinal Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aims This study aimed to explore the relationship between stress‐induced hyperglycemia (SIH) and in‐hospital medical complications in patients with acute stroke. Methods We enrolled 865,765 patients with acute stroke from the Chinese Stroke Center Alliance cohort.
Xintong Song, Yi Ju, Hongqiu Gu, Zhikai Zhu, Zixiao Li, Qian Zhang, Xingquan Zhao   +6 more
wiley   +1 more source

Recurrent lower respiratory tract infections in children

British medical journal, 2018
### What you need to know Acute respiratory infections account for about a third of all paediatric consultations to primary care and 8-18% of acute hospital admissions in the UK.12 Children, especially preschool children, may have up to 6-10 viral colds
F. D. de Benedictis, A. Bush
semanticscholar   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source

Management of respiratory tract infections in young children—A qualitative study of primary care providers’ perspectives

npj Primary Care Respiratory Medicine, 2017
Respiratory tract infections in young children are the most common cause of general practice visits in Australia. Despite the availability of clinical practice guidelines, the treatment and management of respiratory tract infections in young children is ...
Ruby Biezen, Bianca Brijnath, D. Grando, D. Mazza   +3 more
semanticscholar   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

A silent strain: the unseen burden of acute respiratory infections in children

Italian Journal of Pediatrics
The significant impact of acute respiratory tract infections on healthcare systems is well-documented, given their contribution to emergency department admissions, hospitalizations, and increased use of antibiotics and other medications. However, further
Riccardo Boracchini, Benedetta Canova, Pietro Ferrara, Luigi Cantarutti, Carlo Giaquinto, Costanza Di Chiara, Anna Cantarutti   +6 more
doaj   +1 more source

PRINCIPLES OF ANTIBIOTIC TREATMENT OF OUT-OF-HOSPITAL UPPER RESPIRATORY TRACT INFECTIONS IN CHILDREN

Вопросы современной педиатрии, 2012
Special features of etiology of respiratory tract bacterial infections in children in depending of localization of involvement are analyzed in this study. In the article the main principles of rational antibacterial therapy of infectious and inflammatory
A. L. Zaplatnikov, N. V. Koroid, A. A. Girina, I. V. Neyman   +3 more
doaj   +1 more source

Characterisation of antibiotic prescriptions for acute respiratory tract infections in Danish general practice: a retrospective registry based cohort study

npj Primary Care Respiratory Medicine, 2017
Inappropriate use of antibiotics is contributing to the increasing rates of antimicrobial resistance. Several Danish guidelines on antibiotic prescribing for acute respiratory tract infections in general practice have been issued to promote rational ...
R. Aabenhus, M. Hansen, Laura Trolle Saust, L. Bjerrum   +3 more
semanticscholar   +1 more source