Results 81 to 90 of about 834,867 (353)

Dual‐Functional Ingestible Passive Capsules for High‐Throughput Intestinal Sampling with Sealed Containment and Targeted Drug Delivery

open access: yesAdvanced Robotics Research, EarlyView.
To address challenges in high‐throughput intestinal sampling with sealed containment and target drug delivery, we developed a dual‐functional ingestible passive capsule with a dual‐triggered control system based on pH‐response and mechanical actuation.
Libing Huang   +9 more
wiley   +1 more source

Impact of meteorological factors on lower respiratory tract infections in children

open access: yesJournal of International Medical Research, 2015
Objective To evaluate retrospectively the relationship between meteorological factors in Shenmu County, Yulin City, Shaanxi Province, China and the incidence of lower respiratory tract infections in children. Methods Meteorological data (air temperature,
Yonglin Liu   +7 more
semanticscholar   +1 more source

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

open access: yesAdvanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li   +7 more
wiley   +1 more source

Prevention of paediatric respiratory tract infections: emphasis on the role of OM-85

open access: yesEuropean Respiratory Review, 2005
The burden of respiratory tract infections in paediatrics is extremely high, in both industrialised and developing countries. Because adequate diagnosis and causative therapies of these often recurrent respiratory tract infections bear substantial limits,
U. B. Schaad
doaj  

Long‐Term Effects of Xenotransplantation of Human Enteric Glia in an Immunocompetent Rat Model of Acute Brain Injury

open access: yesAdvanced Science, EarlyView.
Acute brain injuries are characterized by extensive tissue damage, resulting in debilitating deficits in patients. Despite considerable progress, cell‐based approaches have yet to identify an ideal candidate. This long‐term study explores the use of an untested cell source – human enteric glia – and a non‐invasive administration route – intranasal ...
Nina Colitti   +11 more
wiley   +1 more source

Systematic review and meta-analysis of respiratory syncytial virus vaccines and their impact on respiratory tract infections in children under 5 years

open access: yesVacciMonitor
Respiratory syncytial virus is the main cause of respiratory tract infections in infants and children. This study systematically reviewed and conducted a meta-analysis of published data on four types of respiratory syncytial virus vaccines and their ...
Charmi Jyotishi   +3 more
doaj  

Analysis of the results of 13 combined pathogen detection in 3966 hospitalised children with acute lower respiratory tract infection

open access: yesScientific Reports
Early and accurate identification of infectious pathogens can facilitate appropriate drug use and reduce both the duration and financial burden associated with hospital stays.
Jiming Li   +3 more
doaj   +1 more source

Respiratory Tract Infections at Mass Gatherings

open access: yesInternational Journal of Infectious Diseases
Introduction: Large-scale events that bring people together, like music festivals, athletic competitions, and religious pilgrimages, can foster the spread of respiratory pathogens by drawing large crowds of people in close quarters.
Prof Jaffar Al-tawfiq
doaj   +1 more source

Respiratory Viral Infection-Induced Microbiome Alterations and Secondary Bacterial Pneumonia

open access: yesFrontiers in Immunology, 2018
Influenza and other respiratory viral infections are the most common type of acute respiratory infection. Viral infections predispose patients to secondary bacterial infections, which often have a more severe clinical course.
Shigeo Hanada   +7 more
doaj   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

open access: yesAdvanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou   +10 more
wiley   +1 more source

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