Results 171 to 180 of about 569,278 (268)

Lost and Found: Is Olfactory Recovery More Promising After COVID‐19 Than Other Causes, Even 2 Years Later?

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Olfactory dysfunction is a hallmark feature of COVID‐19, yet the potential for recovery with long‐standing COVID‐19‐related smell loss (CRSL) remains uncertain, particularly when treatment is initiated years later. This study evaluated olfactory outcomes in patients with CRSL compared with non‐COVID‐19‐related smell loss (non‐CRSL),
John W. Hunsicker, Mabel Berg, Nicolaus Knight, Jessica W. Grayson, Bradford A. Woodworth, Justin H. Turner, Do‐Yeon Cho   +6 more
wiley   +1 more source

Interferon-stimulated gene GALNT2 restricts respiratory virus infections. [PDF]

Nat Microbiol
Ran W, Yang J, Yu S, Hu Q, He Y, Wang S, Wei C, Sun J, Zhu A, Li F, Zhang L, Li P, Hu H, Pan R, Yu Y, Yuan Y, Sun L, Wang Y, Zhang Z, Chen Z, Liu D, Yan Q, Wang D, Yu K, Wang Y, Zhuo J, Zhuang Z, Tao H, Zeng Q, Zhou K, Chen F, Tang W, Zhou Y, Bai R, Xu Y, Li N, Dai J, Zhao H, Park JE, Wang T, Ding Q, Perlman S, Zhao J, Mao Y, Wang S, Zhao J.   +45 more
europepmc   +1 more source

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

Animal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty   +4 more
wiley   +1 more source

Comparative evaluation of five rapid PCR platforms for respiratory virus detection. [PDF]

PLoS One
Smit PW, Man P, Brand H, Breijer S, Wijk MV, Meijer A, Ong DSY.   +6 more
europepmc   +1 more source

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Heterologous immunity and antibody-dependent enhancement in respiratory virus infections. [PDF]

Mol Biol Rep
Nor Isamuddin NH, AbuBakar S, Chin KL, Zainal N.   +3 more
europepmc   +1 more source

Humanized immune system animal models and their recent applications

Animal Models and Experimental Medicine, EarlyView.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli, Rudra B. Amin, A’ishah Bakayoko, Marisa Kruidenier, Sahara Aqui, Sarah J. Skuli, Terence P. Gade   +6 more
wiley   +1 more source

Emerging Respiratory Virus Threats from Influenza D and Canine Coronavirus HuPn-2018. [PDF]

Emerg Infect Dis
Gray GC, Vlasova AN, Lednicky JA, Nguyen-Tien T, Shittu I, Li F.   +5 more
europepmc   +1 more source

Development of a loop‐mediated isothermal amplification‐lateral flow dipstick (LAMP‐LFD) assay and on‐site rapid detection evaluation for Rodentibacter heylii and Rodentibacter pneumotropicus

Animal Models and Experimental Medicine, EarlyView.
This study established a closed‐tube LAMP‐LFD assay for detecting Rodentibacter heylii and Rodentibacter pneumotropicus. The method exhibited high sensitivity (detection limits of 10−5 ng/μL for R. heylii and 10−4 ng/μL for R. pneumotropicus), high specificity, reliable performance with clinical samples, and effective validation in experimental ...
Huiqiong Yan, Sisi Chen, Yuhan Gan, Jing Xing, Yufang Feng, Xin Wen, Jie Fang, Jiangtao Du, Shasang Zhou, Honggang Guo, Xiaoyin Jin, Zhiyuan Wang, Junhao Tao, Lingqun Lu, Qingming Kong, Huazhong Ying, Wei Han, Fangwei Dai   +17 more
wiley   +1 more source

Respiratory Virus Infections and Pulmonary Impairment After Allogeneic Hematopoietic Cell Transplantation. [PDF]

J Infect Dis
Cheng GS, Campbell AP, Campbell AP, Xie H, Ogimi C, Waghmare A, Kuypers J, Nichols WG, Carpenter P, Corey L, Callais C, Sandmaier BM, Stevens-Ayers T, Jerome KR, Chien JW, Leisenring WM, Englund JA, Boeckh M.   +17 more
europepmc   +1 more source