Results 211 to 220 of about 1,320,014 (285)

Probenecid is a dual-acting antiviral/anti-inflammatory therapy for diverse respiratory viruses. [PDF]

Front Pharmacol
Tripp RA, Jones LP, Martin DE.
europepmc   +1 more source

AKAP1 Protects Retinal Ganglion Cells and Preserves Vision by Improving Mitochondrial and Synaptic Health in Glaucomatous Neurodegeneration

Advanced Science, EarlyView.
Intravitreal AAV2‐mediated AKAP1 restoration enhances mitochondrial fusion and biogenesis, improves bioenergetic capacity, and preserves mitochondrial integrity in glaucomatous RGCs. AKAP1 stabilizes presynaptic structure, maintaining synaptic protein expression, and limiting complement‐associated neuroinflammation.
Tonking Bastola, Keun‐Young Kim, Ziyao Shen, Guy A. Perkins, Muna Poudel, Yoonjin Lim, Hyejeong Choi, Soo‐Ho Choi, Mark H. Ellisman, Robert N. Weinreb, Won‐Kyu Ju   +10 more
wiley   +1 more source

Prevalence of respiratory viruses in stable and acute asthma: a systematic review and meta-analysis. [PDF]

Eur Respir Rev
Ananth S, Alimani GS, Boccabella C, Khaleva E, Hansel J, Wang R, Roberts G, Kosmidis C, Bossios A, Vestbo J, Papageorgiou E, Papadopoulos NG, Beloukas A, Mathioudakis AG.   +13 more
europepmc   +1 more source

Correction for Zhang et al., Reconstructing the early spatial spread of pandemic respiratory viruses in the United States. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Environmental cleaning and disinfection practices for respiratory viruses in hospitals and long-term care facilities in the Netherlands. [PDF]

Antimicrob Resist Infect Control
Orsel LM, van Kampen JJA, Haagmans BL, Koopmans MPG, Haanappel CP, van Buul L, Veldkamp KE, van Mansfeld R, Knoester M, Lokate M, Voss A, de Jager HJ, Bowles EC, Voor In 't Holt AF, Severin JA.   +14 more
europepmc   +1 more source

Probe‐Free, Primer‐Programmed Amplicon Encoding Enables Nanopore‐Based Multiplex Detection With Deep Learning Decoding

Advanced Science, EarlyView.
Primer‐programmed amplicon encoding enables reporter‐probe‐free multiplex nucleic acid identification using glass nanopore sensing and deep neural network decoding. ABSTRACT Single‐reaction multiplex nucleic acid testing (NATs) must both co‐amplify multiple targets and distinguish the resulting amplicons within the product mixture.
Md. Ahasan Ahamed, Muhammad Asad Ullah Khalid, Wahid Uz Zaman, Anthony J. Politza, Weihua Guan   +4 more
wiley   +1 more source

RAZOR: a database of PCR primers targeting human respiratory viruses. [PDF]

NAR Genom Bioinform
Gill HM, Mir Q, Srivastava R, Janga SC.
europepmc   +1 more source

Astrocytic Ketogenesis Protects Central Nervous System Injury via CPT1A Stabilization and Epigenetic Regulation

Advanced Science, EarlyView.
A distinct astrocyte subpopulation, enriched at the lesion border, drives CNS repair through enhanced ketone body metabolism. This process promotes neuronal survival and axonal sparing via CPT1A stabilization and H3K9bhb‐dependent epigenetic reprogramming, positioning astrocytic ketogenesis as a promising therapeutic target for tissue regeneration ...
Dishui Pan, Haoming Shu, Rui Gao, Yilong Ren, Wu Ye, Xuhui Ge, Yao Gu, Yufeng Zhu, Xiaokun Wang, Honglin Teng, Xuhui Zhou, Wei Liu, Yang Gao, Jianquan Zhao, Weihua Cai   +14 more
wiley   +1 more source

Immunosenescence and susceptibility to respiratory viruses: a state-of-the-art review. [PDF]

Eur Respir Rev
Fragkou PC, Skevaki C, Moschopoulos CD, Keske Ş, Wozniak H, Malézieux-Picard A, Prendki V, Rello J, ESCMID Study Group for Respiratory Viruses (ESGREV) and the ESCMID Study Group for Infections in the Elderly (ESGIE).   +8 more
europepmc   +1 more source

Gapless Complete Genome and Multi‐Omics Illuminate Immune Adaptation and Host‐Virus Interactions in a Coronavirus Reservoir

Advanced Science, EarlyView.
We present a complete T2T genome assembly for a key bat reservoir. Integrating population genomics, comparative genomics, transcriptomics, single‐cell omics, and functional assays, we resolve previously inaccessible genomic regions and identify evolutionary signatures associated with immune adaptation.
Yuting Wang, Sheng Zhang, Linxia Ouyang, Xin Du, Xin Huang, Zhilin Wang, Huixian Xie, Jiale Tang, Liyi Lou, Wenqing Ling, Weihao Wang, Jiang Zhou, Zhen Liu, Yibo Hu, Fuwen Wei, Guangping Huang   +15 more
wiley   +1 more source