Results 221 to 230 of about 1,320,014 (285)

Editorial: Emerging concepts for respiratory viruses after the pandemic. [PDF]

Front Cell Infect Microbiol
Dimopoulou D, Skevaki C, Can F, Morfin-Sherpa F, Fragkou PC.   +4 more
europepmc   +1 more source

Plasma Membrane Lipid Asymmetry Dynamically Regulates Passive Diffusion

Advanced Science, EarlyView.
Passive diffusion enables hydrophobic molecules to cross the plasma membrane and exert their biological functions. This study demonstrates that plasma membrane lipid asymmetry, dynamically regulated by lipid scrambling, determines membrane permeability to lipophilic molecules and thereby modulates their cellular activities.
Jieming Ping, Wenliang Wang, Jinnuo Xu, Mengyun Yang, Ning Wu   +4 more
wiley   +1 more source

Incidental Detection of Respiratory Viruses in Lung Transplant Donor-Recipient Pairs: Exploratory Associations With Clinical Outcomes in a Post Hoc Analysis. [PDF]

Transpl Infect Dis
Lombardi A, Morlacchi LC, Renisi G, Rosso L, Fumagalli J, Bono P, Righi I, Rossetti V, Liparoti A, Azzarà C, Mangioni D, Alagna L, Celotti A, Alteri C, Abbruzzese C, Callegaro A, Blasi F, Grasselli G, Nosotti M, Bandera A.   +19 more
europepmc   +1 more source

Integrated Multiomic Analysis Reveals an EBV‐Associated MIF–SPP1+ Macrophage Axis Linking Tumor Stemness and Immune Dysfunction in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
This study maps how Epstein–Barr virus reshapes the cellular ecosystem of nasopharyngeal carcinoma. It identifies SPP1+ macrophages as partners of stemness‐associated tumor cells and dysfunctional T cells, links tumor‐derived MIF to macrophage recruitment and programming, and shows that macrophage‐derived SPP1 promotes tumorsphere formation and impairs
Guo‐Ying Liu, Shu‐Hui Lv, Shui‐Qing He, Yao‐Fei Jiang, Xing‐Si Peng, Jian‐Cong Sun, Fen He, Hai‐Yan Qin, Nian Lu, Wei‐Xin Bei, Lin‐Yu Zhao, Wan‐Qin Shen, Ze‐Yu Zhao, Lin Wang, Yan‐Qun Xiang, Wang‐Zhong Li   +15 more
wiley   +1 more source

Citywide indoor air sampling mirrors wastewater and clinical case surveillance of respiratory viruses. [PDF]

Nat Commun
Barbian HJ, Newcomer EP, Bobrovska S, Poretsky RS, Greenwald S, Owens SM, Tiwari A, Berkowitz RJ, Smith S, Wright D, Green SJ, Sanchez Gonzalez D, Lin CY, Horton A, Jarju ML, Wilton R, Hayden MK, Black SR, McSorley VE, Kittner A.   +19 more
europepmc   +1 more source

Ischemic Postconditioning Protects Aged Myocardium Against Ischemia/Reperfusion Injury by Regulating Mitochondrial Dynamics via piR‐4913

Advanced Science, EarlyView.
A tiny RNA tips the scales of cardiac injury in aging. piR‐4913 recruits OGT to Drp1 and drives its O‐GlcNAcylation at Thr604, promoting excessive mitochondrial fission that aggravates ischemia‐reperfusion injury. Ischemic postconditioning silences this pathway to restore mitochondrial balance and protect the aged myocardium, revealing piR‐4913 as a ...
Xiangyu Zhao, Yanchun Li, Nan Li, Juan Zhang, Xiaolong Ma, Fei Yang, Ruihan Long, Yining Tian, Yichen Wang, Shengchao Ma, Huiping Zhang, Yideng Jiang   +11 more
wiley   +1 more source

Emerging Multimodal Point-of-Care Diagnostic Strategies for Rapid Detection and Management of Respiratory Viruses: A State-of-the-Art Review. [PDF]

Diagnostics (Basel)
Hetta HF, Haseeb A, Bukhari SQ, Alatawi Z, Mahrous AJ, Elrggal ME, Masri MA, Kotb AA.   +7 more
europepmc   +1 more source

Lactate Drives Pathological Browning of White Adipose Tissue to Aggravate Sepsis‐Associated Metabolic Disorders in a GPR81‐Dependent Manner

Advanced Science, EarlyView.
Sepsis‐triggered lactate accumulation induces pathological white adipose tissue browning. Lactate activates adipocyte GPR81 to sequentially upregulate CTRP6‐p38 signalling and UCP1 expression. This cascade exacerbates sepsis‐associated metabolic disorders.
Chunliang Zheng, Xiaohua Li, Shuo Li, Chungen Xing, Chun Cao   +4 more
wiley   +1 more source

2-Aminophenylboronic acid-functionalized carbon dots show broad-spectrum antiviral activity against respiratory viruses. [PDF]

Nanoscale Adv
Ahmad MA, Ahmed T, Fahmi MZ, Idris A.
europepmc   +1 more source