Results 1 to 10 of about 140,205 (157)
Preparing for the Next Influenza Season: Monitoring the Emergence and Spread of Antiviral Resistance [PDF]
Infection and Drug Resistance, 2023 Djin-Ye Oh, Jeanette Milde, Youngsun Ham, Julia Patricia Ramos Calderón, Marianne Wedde, Ralf Dürrwald, Susanne C Duwe Robert Koch Institute, Department 1: Infectious Diseases, Unit 17: Influenza and Other Respiratory Viruses, National Influenza Center ...
Oh DY +6 more
doaj +2 more sources
Influenza and antiviral resistance: an overview. [PDF]
Eur J Clin Microbiol Infect Dis, 2020 Influenza affects approximately 1 billion individuals each year resulting in between 290,000 and 650,000 deaths. Young children and immunocompromised individuals are at a particularly high risk of severe illness attributable to influenza and these are also the groups of individuals in which reduced susceptibility to neuraminidase inhibitors is most ...
Lampejo T.
europepmc +4 more sources
Cytomegalovirus in children undergoing haematopoietic stem cell transplantation: a diagnostic and therapeutic approach to antiviral resistance [PDF]
Frontiers in Pediatrics, 2023 Cytomegalovirus (CMV) is a ubiquitous virus which causes a mild illness in healthy individuals. In immunocompromised individuals, such as children receiving haematopoietic stem cell transplantation, CMV can reactivate, causing serious disease and ...
Jocelyn Hume +9 more
doaj +2 more sources
Clinical Implications of Antiviral Resistance in Influenza
Viruses, 2015 Influenza is a major cause of severe respiratory infections leading to excessive hospitalizations and deaths globally; annual epidemics, pandemics, and sporadic/endemic avian virus infections occur as a result of rapid, continuous evolution of influenza ...
Timothy C. M. Li +2 more
doaj +3 more sources
Antiviral resistance of stem cells. [PDF]
Curr Opin Immunol, 2019 Stem cells are important for growth and regeneration given their ability to self-renew and differentiate into mature cells. Resistance to certain viral infections has been established as a phenotype of stem cells, a protection in line with their important physiological function.
Wu X, Kwong AC, Rice CM.
europepmc +4 more sources
Artificial Small RNA-Based Silencing Tools for Antiviral Resistance in Plants [PDF]
Plants, 2020 Artificial small RNAs (art-sRNAs), such as artificial microRNAs (amiRNAs) and synthetic trans-acting small interfering RNAs (syn-tasiRNAs), are highly specific 21-nucleotide small RNAs designed to recognize and silence complementary target RNAs.
Adriana E. Cisneros, Alberto Carbonell
doaj +2 more sources
Strategies and efforts in circumventing the emergence of antiviral resistance against conventional antivirals [PDF]
npj Antimicrobials and ResistanceAntiviral resistance stemming from rapid viral evolution and adaptation is a major challenge faced in treating viral infections. Here, we describe the mechanisms and factors underlying antiviral resistance and their implications to future drug ...
Daryl Zheng Hao Aw +2 more
doaj +2 more sources
Antiviral drug resistance as an adaptive process [PDF]
Virus Evolution, 2016 Antiviral drug resistance is a matter of great clinical importance that, historically, has been investigated mostly from a virological perspective. Although the proximate mechanisms of resistance can be readily uncovered using these methods, larger evolutionary trends often remain elusive.
Nicholas Renzette +2 more
exaly +3 more sources
Influenza viruses – antiviral therapy and resistance
GMS Infectious Diseases, 2017 Influenza is a serious and frequently underestimated, but vaccine preventable disease. The adamantane derivates rimantadine and amantadine and the neuraminidase inhibitors zanamivir and oseltamivir are the only antiviral drugs currently approved in ...
Duwe, Susanne
doaj +5 more sources
Enhanced In Vitro Antiviral Activity of Hydroxychloroquine Ionic Liquids against SARS-CoV-2
Pharmaceutics, 2022 The development of effective antiviral drugs against SARS-CoV-2 is urgently needed and a global health priority. In light of the initial data regarding the repurposing of hydroxychloroquine (HCQ) to tackle this coronavirus, herein we present a ...
Francisco Faísca +5 more
doaj +1 more source