Results 21 to 30 of about 2,451,260 (295)
Suppression of CMV Infection with Letermovir in a Kidney Transplant Patient
European Journal of Case Reports in Internal Medicine, 2020 Infection with cytomegalovirus (CMV) with resistance to ganciclovir (GCV) is a therapeutic challenge in kidney transplant patients, because standard treatment options are nephrotoxic. We report the case of a kidney transplant recipient with GCV-resistant
Uta Köpf +6 more
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BMJ, 1998 The development of effective antiviral drugs is an important biomedical scientific achievement of the late 20th century. Highly potent drugs are now available against herpes viruses, HIV, hepatitis B virus, and influenza virus. This list will extend to papillomaviruses, respiratory viruses, enteroviruses, and hepatitis C virus over the next 5-10 years.
D, Pillay, M, Zambon
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Viruses, 2023 Nirmatrelvir, which targets the SARS-CoV-2 main protease (Mpro), is the first-in-line drug for prevention and treatment of severe COVID-19, and additional Mpro inhibitors are in development.
Karen Anbro Gammeltoft +11 more
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Surveillance for antiviral resistance [PDF]
Influenza and Other Respiratory Viruses, 2012 Please cite this paper as: Zambon. (2012) Surveillance for antiviral resistance. Influenza and Other Respiratory Viruses 7(Suppl. 1), 37–43.In the 10 years since licensure of neuraminidase inhibitor drugs, their use has steadily increased, especially during the pandemic of 2009.
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A Case of Disseminated Infection Caused by Streptococcus equi Subspecies zooepidemicus
Canadian Journal of Infectious Diseases and Medical Microbiology, 2009 Human infections with Streptococcus equi subspecies zooepidemicus, a group C streptococcus, are very rare and are generally associated with contact with horses, and consumption of unpasteurized milk products, goat cheese or pork.
Marie-France Poulin, Guy Boivin
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Analysis of cytomegalovirus resistance mutations and clinical features of CMV infection in immunocompromised children [PDF]
Клиническая микробиология и антимикробная химиотерапияObjective. To determine frequency and spectrum of cytomegalovirus (CMV) resistance mutations to antiviral drugs in immunocompromised children. To study clinical course of resistant CMV infection in this patient population. Materials and Methods. This
Kozhushnaya O.S. +4 more
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Mutations in the cytomegalovirus UL97 gene associated with ganciclovir resistance in recipients of allogeneic hematopoietic stem cell transplants [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2019 Objective. To identify mutations in UL97 gene associated with antiviral drug resistance in recipients of allogeneic hematopoietic stem cells transplants (allo-HSCT). Materials and Methods. A total of 9 HCMV DNA samples were studied.
Demin M.V. +7 more
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Viruses, 2023 The thymidine kinase (TK) and DNA polymerase (pol) genes of the herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2) are two important genes involved in antiviral resistance.
Jungwon Hyun +7 more
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Antiviral resistance of stem cells [PDF]
Current Opinion in Immunology, 2019 Stem cells are important for growth and regeneration given their ability to self-renew and differentiate into mature cells. Resistance to certain viral infections has been established as a phenotype of stem cells, a protection in line with their important physiological function.
Xianfang, Wu +2 more
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Influenza and antiviral resistance: an overview. [PDF]
Eur J Clin Microbiol Infect Dis, 2020 Influenza affects approximately 1 billion individuals each year resulting in between 290,000 and 650,000 deaths. Young children and immunocompromised individuals are at a particularly high risk of severe illness attributable to influenza and these are also the groups of individuals in which reduced susceptibility to neuraminidase inhibitors is most ...
Lampejo T.
europepmc +4 more sources