Results 21 to 30 of about 140,304 (256)
Molecular Basis of Encapsidation of Hepatitis C Virus Genome
Frontiers in Microbiology, 2018 Hepatitis C virus (HCV), a major etiologic agent of human liver diseases, is a positive-sense single-stranded RNA virus and is classified in the Flaviviridae family.
Guoli Shi, Tetsuro Suzuki
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Suppression of CMV Infection with Letermovir in a Kidney Transplant Patient
European Journal of Case Reports in Internal Medicine, 2020 Infection with cytomegalovirus (CMV) with resistance to ganciclovir (GCV) is a therapeutic challenge in kidney transplant patients, because standard treatment options are nephrotoxic. We report the case of a kidney transplant recipient with GCV-resistant
Uta Köpf +6 more
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Viruses, 2023 Nirmatrelvir, which targets the SARS-CoV-2 main protease (Mpro), is the first-in-line drug for prevention and treatment of severe COVID-19, and additional Mpro inhibitors are in development.
Karen Anbro Gammeltoft +11 more
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Antiviral Agents: Discovery to Resistance [PDF]
Viruses, 2020 In the midst of the SARS-CoV-2/Covid-19 outbreak the need for research into, and development of, antiviral agents is brought into sharp focus worldwide for scientists, governments and the public alike [...]
openaire +4 more sources
Mutations in the cytomegalovirus UL97 gene associated with ganciclovir resistance in recipients of allogeneic hematopoietic stem cell transplants [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2019 Objective. To identify mutations in UL97 gene associated with antiviral drug resistance in recipients of allogeneic hematopoietic stem cells transplants (allo-HSCT). Materials and Methods. A total of 9 HCMV DNA samples were studied.
Demin M.V. +7 more
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Viruses, 2023 The thymidine kinase (TK) and DNA polymerase (pol) genes of the herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2) are two important genes involved in antiviral resistance.
Jungwon Hyun +7 more
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A Case of Disseminated Infection Caused by Streptococcus equi Subspecies zooepidemicus
Canadian Journal of Infectious Diseases and Medical Microbiology, 2009 Human infections with Streptococcus equi subspecies zooepidemicus, a group C streptococcus, are very rare and are generally associated with contact with horses, and consumption of unpasteurized milk products, goat cheese or pork.
Marie-France Poulin, Guy Boivin
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Analysis of cytomegalovirus resistance mutations and clinical features of CMV infection in immunocompromised children [PDF]
Клиническая микробиология и антимикробная химиотерапияObjective. To determine frequency and spectrum of cytomegalovirus (CMV) resistance mutations to antiviral drugs in immunocompromised children. To study clinical course of resistant CMV infection in this patient population. Materials and Methods. This
Kozhushnaya O.S. +4 more
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Surveillance for antiviral resistance [PDF]
Influenza and Other Respiratory Viruses, 2012 Please cite this paper as: Zambon. (2012) Surveillance for antiviral resistance. Influenza and Other Respiratory Viruses 7(Suppl. 1), 37–43.In the 10 years since licensure of neuraminidase inhibitor drugs, their use has steadily increased, especially during the pandemic of 2009.
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Frontiers in Microbiology, 2020 Choice of direct acting antiviral (DAA) therapy for Hepatitis C Virus (HCV) in the United Kingdom and similar settings usually requires knowledge of the genotype and, in some cases, antiviral resistance (AVR) profile of the infecting virus.
Carmen F. Manso +15 more
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