Results 41 to 50 of about 2,451,260 (295)
The recent biotechnology breakthrough of cell reprogramming and generation of induced pluripotent stem cells (iPSCs), which has revolutionized the approaches to study the mechanisms of human diseases and to test new drugs, can be exploited to generate ...
Marta Trevisan +6 more
doaj +1 more source
Antiviral potential of cathelicidins [PDF]
The global burden of morbidity and mortality arising from viral infections is high; however, the development of effective therapeutics has been slow.
Davidson, Donald J +4 more
core +1 more source
Influenza antivirals: efficacy and resistance [PDF]
The inaugural conference of the Antiviral Group of the International Society for Influenza and other Respiratory Virus Diseases (ISIRV-AVG) was organised in conjunction with the Oswaldo Cruz Foundation (FIOCRUZ) in Rio de Janeiro, Brazil, in November 2011.
Marilda, Siqueira, Alan, Hay
openaire +2 more sources
Inhibitors of the Hepatitis C Virus Polymerase; Mode of Action and Resistance
The hepatitis C virus (HCV) is a pandemic human pathogen posing a substantial health and economic burden in both developing and developed countries. Controlling the spread of HCV through behavioural prevention strategies has met with limited success and ...
Auda A. Eltahla +4 more
doaj +1 more source
Hepatitis B virus (HBV) infection remains a serious public health concern worldwide despite the availability of an efficient vaccine and the major improvements in antiviral treatments.
Zeineb Belaiba +17 more
doaj +1 more source
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba +29 more
wiley +1 more source
Successive increases in the resistance of Drosophila to viral infection through a transposon insertion followed by a Duplication [PDF]
To understand the molecular basis of how hosts evolve resistance to their parasites, we have investigated the genes that cause variation in the susceptibility of Drosophila melanogaster to viral infection.
Magwire, Michael M +17 more
core +1 more source
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Emergence and Fixing of Antiviral Resistance in Influenza A Via Recombination and Hitch Hiking [PDF]
The dramatic rise of oseltamivir resistance in the H1N1 serotype in the 2007/2008 season and the fixing of H274Y in the 2008/2009 season has raised concerns regarding individuals at risk for seasonal influenza, as well as development of similar ...
Henry L. Niman
core

