Results 101 to 110 of about 8,120 (200)
In the non‐diabetic beta‐cell (top left) activation of glucokinase (bottom left) leads to inhibition of mitochondrial metabolism and thereby impairs insulin secretion. The effect is similar to that of chronic hyperglycaemia as seen in the diabetic beta‐cell (top right).
Matthew Lloyd +9 more
wiley +1 more source
Metabolic Rate of Goldfish (Carassius auratus) in the Face of Common Aquaculture Challenges
This study examined the metabolic rate (MO2, oxygen consumption) of goldfish (Carassius auratus) under normal management conditions in aquaculture.
Lisbeth Herrera-Castillo +6 more
doaj +1 more source
Mitochondrial function predicts dominance status in brown trout
Read the free Plain Language Summary for this article on the Journal blog. Abstract In social hierarchies, winning contests confers better access to food, shelter and reproductive opportunities. Clear dominance relationships are often apparent even when opponents are matched for experience, age, size and other obvious characteristics.
Darryl McLennan +5 more
wiley +1 more source
The energetic consequences of oxygen fluxes in a coral reef fish
Abstract Ocean warming elevates metabolic rates in marine ectotherms but often constrains energetic resources, causing an imbalance between supply and demand. Transient hypoxia is near‐ubiquitous across the world's coral reefs and may exacerbate this imbalance, yet its effects on the energetics of reef fishes remain poorly understood. In this study, we
Daniel M. Ripley +3 more
wiley +1 more source
Read the free Plain Language Summary for this article on the Journal blog. Abstract Many small endotherms employ torpor as a survival strategy to reduce energy expenditure during periods with low food availability and cold temperatures. The expression and physiology of torpor can vary substantially within species because of phenotypic plasticity and ...
Nicholas C. Wu +2 more
wiley +1 more source
Terbinafine and miglustat are mitohormetic compounds that extend lifespan and healthspan. In C. elegans, these FDA‐approved drugs engage both ATFS‐1 and DAF‐16, highlighting a stress‐dependent coordination between mitochondrial and IIS pathways distinct from canonical IIS activation, relevant for healthy aging.
Amélia Lalou +15 more
wiley +1 more source
The data that support the findings of this study are available from the corresponding author upon reasonable request. Some data may not be made available because of privacy or ethical restrictions. Background and Purpose Ventricular arrhythmias are a leading cause of death among patients with cardiovascular diseases and are associated with elevated ...
Felipe de Jesús Salazar‐Ramírez +13 more
wiley +1 more source
We present ‘HomoTherm’, a human heat budget model for simulating humans and related species with diverse traits in diverse environments. It is part of the NicheMapR package for biophysical modelling and is a multi‐part extension of the ‘endoR’ function.
Michael R. Kearney +2 more
wiley +1 more source
Abstract Altitude training enhances haematological adaptations and endurance at sea level, typically requiring exposure to ∼2500 m altitude for 3–4 weeks. Emerging evidence suggests that low‐dose carbon monoxide (CO) inhalation might mimic hypoxia and might be used by elite athletes.
Simone Villanova +3 more
wiley +1 more source
Abstract Type 2 diabetes (T2D) is a global epidemic, with heart failure being the leading cause of premature death. Mitochondrial dysfunction, characterized by impaired energy metabolism, weakened energy transport system and increased oxidative stress, has been proposed as a key contributor to the impairment of contractile function in T2D hearts ...
Toan Pham +4 more
wiley +1 more source

