Results 151 to 160 of about 12,284 (257)

Calciprotein particle‐induced calcium overload triggers mitochondrial dysfunction in endothelial cells

The Journal of Physiology, Volume 604, Issue 11, Page 4186-4207, 1 June 2026.
Abstract figure legend Calciprotein particles (CPPs) are small calcium‐ and phosphate‐containing nanoaggregates associated with the development of vascular disease (CVD) in chronic kidney disease (CKD). Previously, we have shown that CPPs induce endothelial cell (EC) dysfunction, possibly contributing to CVD in CKD, but the underlying molecular ...
Lian Feenstra, Laurent Chatre, Benoit Bernay, Julien Pontin, Mirjam F. Mastik, Azuwerus van Buiten, Dalibor Nakládal, Bastiaan S. Star, Jan‐Luuk Hillebrands, Guido Krenning   +9 more
wiley   +1 more source

Seasonal shifts in mitochondrial and reactive oxygen species metabolism are linked to ultrastructural remodelling in honey bees (Apis mellifera)

The Journal of Physiology, Volume 604, Issue 12, Page 4745-4770, 15 June 2026.
Abstract figure legend Seasonal changes profoundly reshape honey bee mitochondrial metabolism. In winter, bees shift from complex I (CI)‐ to mitochondrial glycerol‐3‐phosphate dehydrogenase (mG3PDH)‐ and complex II (CII)‐linked respiration. Despite lower CI‐linked respiration ATP production is maintained, suggesting increased energetic efficiency in ...
Adèle Léger, Mélanie Aminot, Samuel Robichaud, Sarah Jorissen, Étienne Hébert‐Chatelain, Nicolas Pichaud   +5 more
wiley   +1 more source

In vivo quantification of mitochondrial O2 affinity in human skeletal muscle using 1H‐magnetic resonance spectroscopy of deoxy‐myoglobin

The Journal of Physiology, Volume 604, Issue 12, Page 4876-4888, 15 June 2026.
Abstract figure legend This graphical abstract illustrates a novel, non‐invasive approach to quantify mitochondrial oxygen (O2) affinity in vivo in human skeletal muscle using 1H magnetic resonance spectroscopy (1H‐MRS) of deoxymyoglobin (dMb). During brief arterial occlusion, dMb kinetics were used to simultaneously estimate intracellular oxygen ...
Muhammet Enes Erol, Alexs A. Matias, Corinna F. Serviente, Stephen T. Decker, Rajakumar Nagarajan, Saadallah Ramadan, Yann Le Fur, Song‐Young Park, Gwenael Layec   +8 more
wiley   +1 more source

Novel interactions between the C5‐C5aR1 Axis and IF1: Implications for kidney mitochondrial physiology and ischemia–reperfusion injury

Physiological Reports, Volume 14, Issue 11, June 2026.
Abstract Ischemia‐reperfusion injury (IRI) is a prevalent condition that predominantly afflicts hospitalized patients, inducing acute kidney injury (AKI). In recent years, complement 5 (C5) and its anaphylatoxin receptor C5aR1 have been implicated in driving kidney IRI and loss of function.
Madison McGraw, Amod Sharma, Dinesh Bhattarai, Neriman Gokden, LeeAnn Macmillan‐Crow, Nirmala Parajuli   +5 more
wiley   +1 more source

Diagnosing Metformin Intoxication with High-Resolution Platelet Respirometry: A Case Report. [PDF]

Int J Mol Sci
Sobotka O, Staňková P, Fortunato J, Trčková E, Skořepa P.   +4 more
europepmc   +1 more source

3D skeletal muscle model recapitulating the myostatin knockout phenotypic and mitochondrial metabolic features

Physiological Reports, Volume 14, Issue 12, June 2026.
3D muscle culture reproduces the metabolic characteristics associated with the myostatin knockout phenotype. Abstract 3D cell culture, using a variety of bioengineering techniques, enables muscle cells to be cultured in more structural and functional biomimetic conditions than 2D cell culture.
Barbara Vernus, Elodie Jublanc, Béatrice Chabi, Laurence Pessemesse, Zacharie Cheng‐Boivin, Benoit J. Gentil, Anne Bonnieu, Christelle Koechlin‐Ramonatxo, Bénédicte Goustard   +8 more
wiley   +1 more source

A Case Report of Reversible Mitochondrial Bioenergetic Dysfunction in PBMCs in Anti-GAD65-Associated Cerebellar Ataxia. [PDF]

Cerebellum
Huňarová N, Verešpejová AI, Grófik M, Sivák Š, Kurča E, Kolísek M, Skáčik P.   +6 more
europepmc   +1 more source

Assessment of the feed additive consisting of Lactiplantibacillus plantarum NCIMB 30238 and Pediococcus pentosaceus NCIMB 30237 (1k21008) for all animal species for the renewal of its authorisation (Volac International Ltd)

EFSA Journal, Volume 24, Issue 6, June 2026.
Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the assessment of the application for renewal of authorisation of a preparation of Lactiplantibacillus plantarum NCIMB 30238 and Pediococcus pentosaceus NCIMB 30237 (1k21008) as a technological additive to improve ensiling of fresh material for ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López‐Alonso, Francesca Marcon, Giovanna Martelli, Carlo Nebbia, Alena Pechová, Miguel Prieto‐Maradona, Katerina Theodoridou, Montserrat Anguita, Rosella Brozzi, Nicole Bozzi Cionci, Matteo L. Innocenti, Joana Revez   +21 more
wiley   +1 more source

Characterization of discontinuous ventilation cycles in nymphal Ixodes scapularis. [PDF]

PLoS One
Schofield S, Waters JS, D Y Bandara YMN, Couret J.   +3 more
europepmc   +1 more source

Development of Immunoelectron Microscopy for VASN Detection Using Multiple Models and Identification of VASN as a Key Regulator of Mitochondrial Homeostasis in Hepatocellular Carcinoma Cells

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
We developed an optimized immunoelectron microscopy method (IEM‐VASN) for precise VASN localization, rigorously validated in both gene‐edited cells and knockout mice. Application of this method uncovered distinct mitochondrial enrichment of VASN.
Xiaojing Cheng, Zhouxiang Liao, Qi Zhang, Sha Wen, Hui Li, Biao Li, Meizhen Ou, Yongfeng Li, Xuejing Huang, Zhenyu Song, Lichao Yang, Min He   +11 more
wiley   +1 more source