Results 21 to 30 of about 418 (59)

First report of porcine parainfluenza virus 1 (species Porcine respirovirus 1) in Europe

Transboundary and Emerging Diseases, Volume 68, Issue 4, Page 1731-1735, July 2021., 2021
Abstract Porcine respirovirus 1, also known as Porcine parainfluenza virus 1 (PPIV‐1) was first identified in Hong Kong in 2013, later in the USA and most recently in Chile. Here, we report the first detection of PPIV‐1 outside these three regions. We screened 22 farms in Hungary by testing 15 nasal swab samples obtained from 3‐week‐old piglets (3 ...
Lilla Dénes, Attila Cságola, Kitti Schönhardt, Máté Halas, Norbert Solymosi, Gyula Balka   +5 more
wiley   +1 more source

iPSC screening for drug repurposing identifies anti‐RNA virus agents modulating host cell susceptibility

FEBS Open Bio, Volume 11, Issue 5, Page 1452-1464, May 2021., 2021
FDA‐approved drugs, identified by iPSC screening with Sendai virus, exhibited inhibitory effects on the infection of Huh7 cells by Ebola virus and of Vero E6 cells by SARS‐CoV‐2. These drugs, with efficacy in different combinations of RNA viruses and cells, may have therapeutic potential for RNA virus infections, including newly emerging and mutated ...
Keiko Imamura, Yasuteru Sakurai, Takako Enami, Ran Shibukawa, Yohei Nishi, Akira Ohta, Tsugumine Shu, Jitsutaro Kawaguchi, Sayaka Okada, Thomas Hoenen, Jiro Yasuda, Haruhisa Inoue   +11 more
wiley   +1 more source

Complete Genome Characterization of Eight Human Parainfluenza Viruses from the Netherlands. [PDF]

, 2019
We report the complete genome sequences of eight human parainfluenza viruses (HPIV) belonging to Human respirovirus 1 (HPIV-1), Human respirovirus 3 (HPIV-3), Human rubulavirus 2 (HPIV-2), and Human rubulavirus 4 (HPIV-4).
Arron, Georgina, Cotten, Matthew, GeurtsvanKessel, Corine H, Huisman, Robin C, Koopmans, Marion PG, Molenkamp, Richard, Phan, My VT   +6 more
core   +2 more sources

Assessment of Viral Targeted Sequence Capture Using Nanopore Sequencing Directly from Clinical Samples [PDF]

, 2020
Shotgun metagenomic sequencing (SMg) enables the simultaneous detection and characterization of viruses in human, animal and environmental samples. However, lack of sensitivity still poses a challenge and may lead to poor detection and data acquisition ...
Cassidy, Hayley, Couto, Natacha, Friedrich, Alex W, Harlizius, Juergen, Lambrecht, Claudia, Lizarazo, Erley, Loebert, Sandra, Niesters, Hubert G M, Peter, Silke, Rossen, John W A, Schuele, Leonard, Schuetze, Sabine, Strutzberg-Minder, Katrin   +12 more
core   +1 more source

UK circulating strains of human parainfluenza 3: an amplicon based next generation sequencing method and phylogenetic analysis. [PDF]

, 2018
Background: Human parainfluenza viruses type 3 (HPIV3) are a prominent cause of respiratory infection with a significant impact in both pediatric and transplant patient cohorts.  Currently there is a paucity of whole genome sequence data that would allow
Emmott, Edward, Goodfellow, Ian, Jalal, Hamid, Popay, Ashley, Ranellou, Kyriaki, Smielewska, Anna   +5 more
core   +1 more source

Comprehensive Detection of Candidate Pathogens in the Lower Respiratory Tract of Pediatric Patients With Unexpected Cardiopulmonary Deterioration Using Next-Generation Sequencing [PDF]

, 2020
Objectives: Next-generation sequencing has been applied to the investigation of microorganisms in several clinical settings. We investigated the infectious etiologies in respiratory specimens from pediatric patients with unexpected cardiopulmonary ...
103497, 103498, 103499, 103500, 103501, 103502, 103503, 103504, 103505, 103506, 103507, Horiba, Kazuhiro, Ikeyama, Takanari, Ito, Yoshinori, Kawabe, Shinji, Kawada, Jun-ichi, Okumura, Toshihiko, Suzuki, Takako, Takeuchi, Suguru, Torii, Yuka, Wada, Sho, Yamaguchi, Makoto   +21 more
core   +1 more source

Predictors of human-infective RNA virus discovery in the United States, China, and Africa, an ecological study [PDF]

, 2022
BACKGROUND: The variation in the pathogen type as well as the spatial heterogeneity of predictors make the generality of any associations with pathogen discovery debatable.
Chase-Topping, Margo, Guo, Chuan-Guo, Woolhouse, Mark E.J., Zhang, Feifei   +3 more
core   +1 more source

Analysis of Paramyxovirus Transcription and Replication by High-Throughput Sequencing. [PDF]

, 2019
We have developed a high-throughput sequencing (HTS) workflow for investigating paramyxovirus transcription and replication. We show that sequencing of oligo(dT)-selected polyadenylated mRNAs, without considering the orientation of the RNAs from which ...
Davison, AJ, Goodbourn, S, Hughes, DJ, Modha, S, Randall, RE, Vattipally, S, Wignall-Fleming, EB   +6 more
core   +4 more sources

Macroevolution of virulence shifts in human-infective RNA virus species [PDF]

, 2023
Study Objectives: To determine the frequency and distribution of virulence shifts across 40 viral genera that include human-infective RNA virus species using evolutionary discrete trait models. Methods: An inhouse database containing RNA-dependent RNA
Dalhuisen, Thomas
core   +1 more source

Annual (2023) taxonomic update of RNA-directed RNA polymerase-encoding negative-sense RNA viruses (realm Riboviria: kingdom Orthornavirae: phylum Negarnaviricota) [PDF]

, 2023
In April 2023, following the annual International Committee on Taxonomy of Viruses (ICTV) ratification vote on newly proposed taxa, the phylum Negarnaviricota was amended and emended.
Abe, Junya, Adkins, Scott, Alkhovsky, Sergey V, Avšič-Županc, Tatjana, Ayllón, María A, Bahl, Justin, Balkema-Buschmann, Anne, Ballinger, Matthew J, Beer, Martin, Bejerman, Nicolas, Bergeron, Éric, Biedenkopf, Nadine, Blair, Carol D, Blasdell, Kim R, Blouin, Arnaud G, Bradfute, Steven B, Briese, Thomas, Brown, Paul A, Buchholz, Ursula J, Buchmeier, Michael J, Bukreyev, Alexander, Burt, Felicity, Büttner, Carmen, Calisher, Charles H, Cao, Mengji, Casas, Inmaculada, Chandran, Kartik, Charrel, Rémi N, et al, Hepojoki, Jussi, Kuhn, Jens H, Kumar Baranwal, Virendra   +31 more
core   +1 more source