Results 121 to 130 of about 1,787,447 (311)
, 2011 This study investigated whether methylphenidate is effective in improving response inhibition in children with Attention Deficit Hyperactivity Disorder (ADHD).
Rachel Brackenridge +7 more
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Neural Correlates of Response Inhibition and Conflict Control on Facial Expressions
, 2018 Response inhibition and conflict control on affective information can be regarded as two important emotion regulation and cognitive control processes.
Shi, Jiannong +5 more
core +1 more source
Frontiers in Human NeuroscienceIntroductionLower sensitivity (LS) to acute alcohol promotes hazardous alcohol use, increasing risk for alcohol use disorder (AUD). Compared to peers with high sensitivity (HS), LS individuals exhibit amplified responses to alcohol cues and difficulty ...
Roberto U. Cofresí +7 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
, 2009 Superior response inhibition is an essential component of the advanced cognitive abilities of gifted children. This study investigated response inhibition in intellectually gifted children by recording event-related brain potentials (ERPs) during a Go ...
Duan, Xiaoju +6 more
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Response Inhibition in Smokers
Advances in Psychological Science, 2015 近期研究发现，吸烟会使个体的反应抑制能力受到一定程度的影响。与不吸烟的健康人群相比，吸烟者在测量反应抑制能力的Go/NoGo任务和Stop-Signal任务上的虚报率较高，反应时间较长；吸烟者的反应抑制能力在反应抑制加工阶段受到影响，而在冲突监控阶段并未与正常被试表现出差异；另外，研究还发现，与不吸烟者相比，吸烟者左侧丘脑、左侧额中回和左侧前扣带回灰质体积较小。尼古丁的摄入对前额叶和中脑边缘多巴胺系统的影响可能是导致吸烟者反应抑制能力受到影响的原因。但是，一些研究并未发现吸烟对反应抑制能力存在影响，这可能与实验任务以及研究对象的选取有关。比较不同香烟剥夺状态下个体的反应抑制能力、比较吸烟者与其他药物成瘾者（酒精、毒品）反应抑制能力的差异并且比较使用双选择oddball范式与 Go/NoGo 任务和 ...
Xin ZHAO +3 more
openaire +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
, 2009 This study investigated the impact of auditory-induced emotion on response inhibition. Fifty kinds of positive, neutral, and negative sounds were used as emotional materials whose presentation was followed by a Go/Nogo task. Event-related potentials were
Yuan, Jiajin +3 more
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