Results 121 to 130 of about 13,505,920 (341)

The Impact of Dexamphetamine Treatment for Obesity on Executive Function: A Double-Blind Randomised Controlled Pilot Study

Brain Sciences
Background: Amphetamines increase dopamine levels in mid-brain regions which, in turn, impact top-down executive function. Repeated exposure is linked to substance use disorders.
Antoinette Poulton, Natalie Gauci, Hazer Khalifa, Emily J. Hibbert, Alison S. Poulton   +4 more
doaj   +1 more source

Fluctuating disinhibition: Implications for the understanding and treatment of alcohol and other substance use disorders

Frontiers in Psychiatry, 2013
Disinhibition is present in various maladaptive behaviours, including substance use disorders. Most previous research has assumed that disinhibition is a psychological construct that is relatively stable within individuals.
Andrew eJones, Paul eChristiansen, Chantal eNederkoorn, Katrijn eHouben, Matt eField   +4 more
doaj   +1 more source

Altered neural connectivity during response inhibition in adolescents with attention-deficit/hyperactivity disorder and their unaffected siblings

NeuroImage: Clinical, 2015
Introduction Response inhibition is one of the executive functions impaired in attention-deficit/hyperactivity disorder (ADHD). Increasing evidence indicates that altered functional and structural neural connectivity are part of the neurobiological basis
Daan van Rooij, C. Hartman, M. Mennes, J. Oosterlaan, B. Franke, N. Rommelse, D. Heslenfeld, S. Faraone, J. Buitelaar, P. Hoekstra   +9 more
semanticscholar   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Effect of foreknowledge on neural activity of primary go responses relates to response stopping and switching

Frontiers in Human Neuroscience, 2015
Being able to stop (or inhibit) an action rapidly as in a stop-signal task is an essential human ability. Previous studies showed that when a pre-stimulus cue warned of the possible need to stop a response in an upcoming trial, participants’ response ...
Benjamin eXu, Sarah eLevy, John eButman, Dzung ePham, Dzung ePham, Leonardo G Cohen, Marco eSandrini, Marco eSandrini   +7 more
doaj   +1 more source

Comparison of executive functions in addicted young people who referred to addiction treatment camps with students

Cogent Psychology, 2020
Background and aim: Cerebral areas related to executive functions, during adolescence and early youth encounter with structural and functional changes and fluctuations that expose adolescents to many problems including drug abuse.
Abdollah Salmani, Mghsoud Nader pilehroud, Maryam jammali   +2 more
doaj   +1 more source

No Effects of Bilateral tDCS over Inferior Frontal Gyrus on Response Inhibition and Aggression

PLoS ONE, 2015
Response inhibition is defined as the capacity to adequately withdraw pre-planned responses. It has been shown that individuals with deficits in inhibiting pre-planned responses tend to display more aggressive behaviour. The prefrontal cortex is involved
Franziska Dambacher, T. Schuhmann, J. Lobbestael, A. Arntz, Suzanne Brugman, A. Sack   +5 more
semanticscholar   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Transforming growth factor-beta stimulation of lung fibroblast prostaglandin E2 production. [PDF]

, 1989
Transforming growth factor-beta (TGF beta) stimulated the production of total protein, collagen, and fibronectin by normal human lung fibroblasts.
Diaz, Arturo, Jimenez, Sergio A., Varga, John   +2 more
core   +1 more source

UCN-01 enhances cytotoxicity of irinotecan in colorectal cancer stem-like cells by impairing DNA damage response [PDF]

, 2016
Colorectal cancer (CRC) is one of the most common and lethal cancers worldwide. Despite recent progress, the prognosis of advanced stage CRC remains poor, mainly because of cancer recurrence and metastasis.
Biffoni, Mauro, BUCCARELLI, MARIACHIARA, Cappellari, Marianna, De Luca, Gabriele, Fanciulli, Maurizio, Goeman, Frauke, Melucci, Elisa, PILOZZI, Emanuela, Ricci Vitiani, Lucia, SIGNORE, MICHELE   +9 more
core   +1 more source