Results 61 to 70 of about 1,756,114 (279)

Cyclic nucleotide-gated channels: structural basis of ligand efficacy and allosteric modulation [PDF]

open access: yes, 1997
Most working proteins, including metabolic enzymes, transcription regulators, and membrane receptors, transporters, and ion channels, share the property of allosteric coupling. The term 'allosteric' means that these proteins mediate indirect interactions
Lester, Henry A.   +2 more
core   +1 more source

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis   +13 more
wiley   +1 more source

Optimization of shape memory alloy braces for concentrically braced steel braced frames

open access: yesOpen Engineering, 2019
Expanding the use of smart braced frames to govern the seismic response of structures by providing ductility and elasticity has been hampered and delayed by cost indexes.
Babaei Sasan, Zarfam Panam
doaj   +1 more source

Boundary condition effect on response modification factor of X-braced steel frames

open access: yesHBRC Journal, 2018
Design of the structures to resist seismic force depends on the theory of dissipation in elastic energy that already exists in response modification factor “R-factor”.
Walid A. Attia, Masood M.M. Irheem
doaj   +1 more source

Thurstonian Scaling of Compositional Questionnaire Data [PDF]

open access: yes, 2016
To prevent response biases, personality questionnaires may use comparative response formats. These include forced choice, where respondents choose among a number of items, and quantitative comparisons, where respondents indicate the extent to which ...
Anna Brown   +5 more
core   +2 more sources

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li   +6 more
wiley   +1 more source

Investigating effects of boundary conditions on the evaluation of R-factor of un-braced steel frames

open access: yesHBRC Journal, 2017
Design of Structures to resist seismic load depends on the theory of dissipation in elastic of energy that already exists in response modification factor “R-factor”.
Masood M.M. Irheem, Walid A. Attia
doaj   +1 more source

Effect of Etanercept on anti-carbamylated protein antibodies in patients with rheumatoid arthritis [PDF]

open access: yes, 2015
Rheumatoid Arthritis (RA) is a systemic, chronic inflammatory disease characterized by inflammation of synovial joints and production of autoantibodies such as Rheumatoid Factor and antibodies directed against modified proteins - i.e.
Alessandri, Cristiano   +4 more
core   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed   +5 more
wiley   +1 more source

RNA methylation pattern and immune microenvironment characteristics mediated by m6A regulator in ischemic stroke

open access: yesFrontiers in Genetics, 2023
Background: Ischemic stroke (IS) is a highly heterogeneous disease. Recent studies have shown that epigenetic variables affect the immune response. However, only a few studies have examined the relationship between IS and m6A immunoregulation. Therefore,
Kejuan Jia   +10 more
doaj   +1 more source

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