Results 121 to 130 of about 1,717,018 (297)

Endogenous transforming growth factor β1 suppresses inflammation and promotes survival in adult CNS

, 2007
Transforming growth factor β1 (TGFβ1) is a pleiotropic cytokine with potent neurotrophic and immunosuppressive properties that is upregulated after injury, but also expressed in the normal nervous system.
Bauer, K, Koppius, A, Makwana, M, Cuthill, D, Ormsby, I, Jones, LL, Bueringer, D, Friedrichsen, S, Hristova, M, Heuer, H, Bohatschek, M, Doetschman, T, Raivich, G   +12 more
core  

Reduction of Forced Response Levels for Bladed Disks by Mistuning: Overview of the Phenomenon

, 2011
The newly revealed phenomenon of reduction of forced response levels in a mistuned bladed disk to levels significantly (e.g., by a factor of 2 and more) lower than that of its tuned counterpart is studied in detail on an example of a realistic bladed ...
E. P. Petrov
core   +1 more source

Response Reduction Factor for Industrial Structures [PDF]

HELIX, 2019
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Characterization of sigma factors of Sinorhizobium meliloti involved in stress response

, 2011
Cavalcanti de Lucena DK. Characterization of sigma factors of Sinorhizobium meliloti involved in stress response. Bielefeld: Universität Bielefeld; 2011.Alternative sigma factors play an important role in that they can respond with transcriptional ...
Cavalcanti de Lucena, Daniella Karine
core  

Reduction of Forced Response Levels for Bladed Discs by Mistuning: Overview of the Phenomenon

, 2010
The newly-revealed phenomenon of reduction of forced response levels in a mistuned bladed disc to levels significantly (e.g. by a factor of two and more) lower than that of its tuned counterpart is studied in detail on an example of a realistic bladed ...
E. P. Petrov
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

EVALUATION OF RESPONSE REDUCTION FACTOR IN NON-STATIONARY ELASTIC RESPONSE

Journal of Structural and Construction Engineering (Transactions of AIJ), 2018
Yuri OTSUKA, Ying ZHU, Miei ITO, Daisuke ODE, Hisahiro HIRAISHI   +4 more
openaire   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source