Results 111 to 120 of about 2,019,906 (300)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Investigation of the Effects of the 2023 Kahramanmaraş Earthquakes on Low- and Medium-Rise Reinforced Concrete Buildings

open access: yesBuildings
On 6 February 2023, two major earthquakes occurred approximately nine hours apart in the Pazarcık (Mw = 7.7) and Elbistan (Mw = 7.6) districts of Kahramanmaraş, Türkiye.
Alperen Türkay
doaj   +1 more source

The magnetic excitation spectra in BaFe$_{2}$As$_{2}$: a two-particle approach within DFT+DMFT

open access: yes, 2011
We study the magnetic excitation spectra in the paramagnetic state of BaFe$_{2}$As$_{2}$ from the \textit{ab initio} perspective. The one-particle excitation spectrum is determined within the combination of the density functional theory and the dynamical
Gabriel Kotliar   +3 more
core   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Characteristics of Jerk Response Spectra for Elastic and Inelastic Systems

open access: yesShock and Vibration, 2015
Jerk is the time rate of acceleration and mainly represents the nonstationary component in high frequency band of the earthquake wave. The study on jerk and its response spectra can enhance the recognition of the nonstationary ground motion.
Haoxiang He, Ruifeng Li, Kui Chen
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Vibration simulator studies for the development of passenger ride comfort criteria [PDF]

open access: yes, 1975
A test program to determine the total discomfort associated with vehicle vibration is described. The program utilizes a three-degree-of-freedom vibration simulator to determine the effects of multifrequency and multiaxis vibration inputs. The approach to
Dempsey, T. K., Leatherwood, J. D.
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Bragg Spectroscopy of ultracold atoms loaded in an optical lattice

open access: yes, 2005
We study Bragg spectroscopy of ultra-cold atoms in one-dimensional optical lattices as a method for probing the excitation spectrum in the Mott insulator phase, in particular the one particle-hole excitation band.
Blakie, P. Blair   +4 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy