Results 101 to 110 of about 2,019,906 (300)
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
GW quasi-particle spectra from occupied states only
We introduce a method that allows for the calculation of quasi-particle spectra in the GW approximation, yet avoiding any explicit reference to empty one-electron states. This is achieved by expressing the irreducible polarizability operator and the self-
Geoffrey Stenuit +6 more
core +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
The development of a suitable set of input ground motions is crucial for dynamic time history analyses. The US Nuclear Regulatory Commission (NRC) requires that these motions generate response spectra closely matching the plant’s design spectrum ...
Luis A. Montejo
doaj +1 more source
Propose of Capacity Spectrum Method by Nonlinear Earthquake Response Analysis
Abstract In this paper, a method on deducing the capacity spectrum based on nonlinear earthquake response analysis will be introduced. Damage assessment of general building draws the capacity spectrum through the Push-over analysis and the intersection point of capacity spectrum and demand spectrum is seen as performance point.
You Jin-Sun, Yang Won-Jik, Yi Waon-Ho
openaire +2 more sources
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Dynamic site response is usually implemented using an equivalent-linear approach through analyses based on time-histories or random vibration theory (RVT).
Margarita A. Chi-Miranda +1 more
doaj +1 more source
Some problems in the application of spectrum techniques to strong-motion earthquake analysis [PDF]
A comparison of analog and digital computation of strong-motion earthquake response spectra is made, and it is shown that the preference as to method will depend mainly on availability of computing equipment.
Hudson, D. E.
core +1 more source
Optical Absorption Spectra of Bipolarons
The absorption of large bipolarons is investigated using the path-integral method. The response of a bipolaron to an external electromagnetic field is derived in the framework of the memory-function approach.
A. S. Alexandrov +28 more
core +2 more sources
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source

