Results 81 to 90 of about 2,019,906 (300)

The scalar perturbation spectral index n_s: WMAP sensitivity to unresolved point sources [PDF]

, 2007
Precision measurement of the scalar perturbation spectral index, n_s, from the Wilkinson Microwave Anisotropy Probe temperature angular power spectrum requires the subtraction of unresolved point source power. Here we reconsider this issue.
A. J. Banday, F. K. Hansen, H. K. Eriksen, K. M. Górski, K. M. Huffenberger, Trushkin S. A.   +5 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Design response spectrum based on shock-waveform decomposition method

Soil Dynamics and Earthquake Engineering
This study applies the shock-waveform (SW) decomposition method, originally developed for mechanical shock analysis, to earthquake ground motions. It reveals a general shape similarity between the envelope of the Pseudo-Spectral Accelerations (PSAs) of SW decomposed components and the PSA of the corresponding ground motion.
Yunji Fu, Q.M. Li
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Comparative Study of Different Linear Analysis for Seismic Resistance of Buildings According to Eurocode 8

Vibration
Structural design in Europe should strongly follow EN 1998-1 or so called Eurocode 8 (EC8), for a seismic resistance assessment of structures. Eurocode 8 recommends two linear methods and two nonlinear methods.
Ivelin Ivanov, Dimitar Velchev
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Sky reconstruction from transit visibilities: PAON-4 and Tianlai Dish Array

, 2016
The spherical harmonics $m$-mode decomposition is a powerful sky map reconstruction method suitable for radio interferometers operating in transit mode. It can be applied to various configurations, including dish arrays and cylinders.
Ansari, Reza, Campagne, Jean-Eric, Chen, Xuelei, Magneville, Christophe, Wu, Fengquan, Zhang, Jiao   +5 more
core   +3 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Nonlinear vibration analysis of vehicle–bridge interaction for condition monitoring

Journal of Low Frequency Noise, Vibration and Active Control, 2019
In this paper, we investigate vehicle–bridge interactions and propose a new method for assessing bridge conditions based on nonlinear vibration analysis.
Dejian Meng, Feng Xiao, Lijun Zhang, Xiaotian Xu, Gang S Chen, Wael Zatar, J Leroy Hulsey   +6 more
doaj   +1 more source

Aging State Detection of Viscoelastic Sandwich Structure Based on ELMD and Sensitive IA Spectrum Entropy

IEEE Access, 2019
Viscoelastic sandwich structure is playing an important role in mechanical equipment, but therein viscoelastic material inevitably suffers from aging which affects structural service performance and the whole performance of equipment.
Jinxiu Qu, Changquan Shi
doaj   +1 more source