Results 71 to 80 of about 2,019,906 (300)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Precise response functions in all-electron methods: Application to the optimized-effective-potential approach [PDF]

, 2012
The optimized-effective-potential (OEP) method is a special technique to construct local Kohn-Sham potentials from general orbital-dependent energy functionals. In a recent publication [M. Betzinger, C. Friedrich, S. Bl\"ugel, A. G\"orling, Phys. Rev.
Betzinger, Markus, Blügel, Stefan, Friedrich, Christoph, Görling, Andreas   +3 more
core   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Stochastic Subspace Method for Experimental Modal Analysis

MATEC Web of Conferences, 2016
The formula of stochastic subspace identification method is deduced in details and the program is written out. The two methods are verified by a vibration test on a 5-floor rigid frame model.
Liu Dazhi, Xiang Shuhong, Fan Shichao, Li Ye, Liu Zheng, Sun Jiangang   +5 more
doaj   +1 more source

Multifractal characterization of stochastic resonance

, 2000
We use a multifractal formalism to study the effect of stochastic resonance in a noisy bistable system driven by various input signals. To characterize the response of a stochastic bistable system we introduce a new measure based on the calculation of a ...
A. Arnéodo, A. Neiman, A. Neiman, A. Neiman, A. Neiman, A. Neiman, A. S. Pikovsky, A. Silchenko, Alexander Silchenko, B. McNamara, B. Shulgin, C. Heneghan, C. Nicolis, C. Nicolis, Chin-Kun Hu, E. Bacry, Hu Gang, J. F. Muzy, J. F. Muzy, J. F. Muzy, J. J. Collins, J. J. Collins, J. J. Collins, J. K. Douglass, J. W. C. Robinson, K. O. Wiklund, L. Gammaitoni, L. Gammaitoni, L. Gammaitoni, L. Schimansky-Geier, M. C. Cross, M. E. Inchiosa, M. H. Choi, M. I. Dykman, P. Ch. Ivanov, P. Ch. Ivanov, P. E. Greenwood, P. Jung, P. Jung, R. Benzi, R. Benzi, S. Fauve, S. Mallat, S. Mallat, T. C. Halsey, T. Zhou, V. S. Anishchenko, V. S. Anishchenko   +47 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

The Application of Continuous Wavelet Transform Based Foreground Subtraction Method in 21 cm Sky Surveys

, 2013
We propose a continuous wavelet transform based non-parametric foreground subtraction method for the detection of redshifted 21 cm signal from the epoch of reionization.
An, Tao, Chen, Wen, Gu, Junhua, Wang, Jingying, Xu, Haiguang   +4 more
core   +1 more source

Real-Time Propagation TDDFT and Density Analysis for Exciton Couplings Calculations in Large Systems [PDF]

, 2019
Photo-active systems are characterized by their capacity of absorbing light energy and transforming it. Usually, more than one chromophore is involved in the light absorption and excitation transport processes in complex systems.
Jornet-Somoza, Joaquim, Lebedeva, Irina
core   +5 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

The Quasinormal Mode Spectrum of a Kerr Black Hole in the Eikonal Limit

, 2010
It is well established that the response of a black hole to a generic perturbation is characterized by a spectrum of damped resonances, called quasinormal modes; and that, in the limit of large angular momentum ($l \gg 1$), the quasinormal mode frequency
B. Mashhoon, C. W. Misner, E. Berti, J. Natário, K. D. Kokkotas, M. Abramowitz, S. Chandrasekhar, S. L. Detweiler, Sam R. Dolan   +8 more
core   +1 more source