Results 101 to 110 of about 1,569,701 (307)

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Optimization of sanding parameters using response surface methodology

Maderas: Ciencia y Tecnología, 2017
The main objective of this work is to develop a mathematical model to evaluate optimum sanding conditions of Europen black pine (Pinus nigra). Samples were sanded using different of grit size, feed rate, cutting speed and depth of cut.
Ender Hazir, Kücük Hüseyin Koc, Salim Hiziroglu   +2 more
doaj  

Influence of Gravading Process Parameters on Physicochemical Attributes of Rainbow Trout (Oncorhynchus mykiss) Gravads

Acta Universitatis Cibiniensis. Series E: Food Technology
Gravads are a traditional type of Scandinavian delicatessen frequently made from salmon. Developing a gravading technology by using other fish like farmed rainbow trout may make gravads more popular in countries without a tradition in this field. The aim
Michalczyk Magdalena, Maciejaszek Ireneusz   +1 more
doaj   +1 more source

Optimization of the PDMS/biochar nanocomposite membranes using the response surface methodology

Science and Engineering of Composite Materials, 2018
To improve the separation performance of the polydimethylsiloxane (PDMS)/bark biochar (BB) nanocomposite membranes used for alcohol/water separation, the preparation conditions of these composite membranes were analyzed and optimized.
Lan Yongqiang, Yan Ning, Wang Weihong
doaj   +1 more source

Otimização das condições de extração de saponinas em Ampelozizyphus amazonicus usando planejamento experimental e metodologia de superfície de resposta

Química Nova, 2011
This works describes the use of experimental design and surface response methodology for optimization of saponin extraction from Ampelozizyphus amazonicus.
Fabiane M dos Santos, Jersika C Simões, Jefferson R. A Silva, Rosangela C Barthus, Ronei J Poppi, Ana C. F Amaral   +5 more
doaj   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Polynomial Regression and Response Surface Methodology: Theoretical Non-Linearity, Tutorial and Applications for Information Systems Research

Australasian Journal of Information Systems, 2019
Information systems (IS) studies regularly assume linearity of the variables and often disregard the potential non-linear theoretical interrelationships among the variables.
Darshana Sedera, Maura Atapattu
semanticscholar   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Optimization of chlorophyll extraction from mulberry leaves using response surface methodology

浙江大学学报. 农业与生命科学版, 2012
Chlorophyll plays an important role in our everyday life. It is used not only as an annexing agent in medicinal and calleidic products but also as an unartificial food coloring agent.
CHEN Shao-yuan, LÜ Zhen-er, DONG Feng-li, MAO Bi-zeng   +3 more
doaj   +1 more source

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma, Nathan Pavey, Yukiko Tsuji, Amirul Ab Ghapar, Mehdi A.J. van den Bos, Bronwen Orden, Grace Lee, Linda Mekhael, Julie Ryder, Cláudia Santos Silva, David McDonald, Fakhria Kakar, Con Yiannikas, Matthew C. Kiernan, David A. Brown, Parvathi Menon, Steve Vucic   +16 more
wiley   +1 more source