Results 81 to 90 of about 12,593,396 (297)
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Comparison of response surface methodology and the Nelder and Mead simplex method for optimization in microsimulation models [PDF]
Microsimulation models are increasingly used in the evaluation of cancer screening. Latent parameters of such models can be estimated by optimization of the goodness-of-fit.
Neddermeijer, H.G. +4 more
core
Response surface methodology for estimating missing values in a pareto genetic algorithm used in parameter design [PDF]
, 2017 We present an improved Pareto Genetic Algorithm (PGA), which finds solutions to problems of robust design in multi-response systems with 4 responses and as many as 10 control and 5 noise factors.
Chaigneau, Sergio +3 more
core +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Microbiology Indonesia, 2015 Surfactin is a lipopeptide biosurfactant that show potential biomedical application due to its activities such as antiviral, antibacterial, antifungi, anticancer, and antimycoplasma. Bacillus amyloliquefaciens MD4-12, isolated from oil-contaminated soil,
AHMAD WIBISANA +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Coagulation: Determination of key operating parameters by multi-response surface methodology using desirability functions [PDF]
, 2019 The clarification process removes colloidal particles that are suspended in waste water. The efficiency of this process is influenced by a series of inputs or parameters of the coagulation process, of which the most commonly used are initial turbidity ...
González, Eliseo P. Vergara [0000-0002-0083-6401] +14 more
core +1 more source
Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
FEBS Open Bio, EarlyView.Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
Mathematical Modelling Of Backward Extraction Mixed Reverse Micelle Of Amoxicillin By Surface Response Methodology (RSM) [PDF]
, 2017 One of important factor in reverse micelle extraction is backward transfer. It is important to investigate the favourable conditions for backward transfer from reverse micellar phase to an organic phase. The back extraction of amoxicillin was studied
Siti Norazimah, Mohamad Aziz +1 more
core +2 more sources
Czech Journal of Food Sciences, 2017 The effects of defatted hemp cake added to corn grits (at ratios of 0, 5, and 10% DM), the moisture content of the mixtures (15, 20, and 25%) and the temperature in the extruder ejection zone (150, 165, and 180°C) on the physical properties of extruded ...
Antun Jozinović +6 more
doaj +1 more source