Results 81 to 90 of about 1,638,463 (351)

A Genetic Algorithm with Design of Experiments Approach to Predict the Optimal Process Parameters for FDM [PDF]

, 2005
This paper describes a Genetic Algorithm (GA) with Design of Experiments (DoE) approach to predict the optimized surface roughness and porosity characteristics of the parts produced using ABS material on stratasys FDM 2000 machine.
Arumaikkannu, G., Gowri, S., Uma Maheshwaraa, N.   +2 more
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Causes of atmospheric temperature change 1960-2000: A combined attribution analysis [PDF]

, 2003
We investigate the causes of temperature change over the last four decades, both near the surface and in the free atmosphere, using a coupled atmosphere/ocean general circulation model, HadCM3, which requires no flux correction.
Allen, Gareth S. Jones, Gillett, Gordon, Hasselmann, Hegerl, Hill, Hoyt, Lean, Mitchell, North, North, Parker, Parker, Peter A. Stott, Pope, Santer, Sato, Simon F. B. Tett, Stott, Stott, Stott, Stott, Tett, Tett, Tett   +25 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Optimized microwave-assisted azadirachtin extraction using response surface methodology

Heliyon
The neem tree (Azadirachta indica A. Juss) is grown mainly for shade, fuel, and numerous non-timber forest products using its leaves, fruit, and bark.
Robinson Martínez-Castro, Jiress Flórez-Santiago, Roger Valle-Molinares, Julián Cabrera-Barraza, Fabián Espitia-Almeida   +4 more
doaj   +1 more source

Optimization of ß-galactosidase Production by Response Surface Methodology [PDF]

, 2011
â-galactosidase production is carried out using lactose or lactose rich substrates like whey. Tamarind seed powder has not been reported as a substrate for production of this enzyme before. In this study, statistical optimization of medium components for
Raghunath Rashmi, ., Siddalingamurthy, K.R.   +1 more
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Optimizing Fermentation Medium to Produce Cyclosporin a Using Response Surface Methodology [PDF]

, 2012
Response surface methodology (RSM) is a three factorial model which illustrates the relationship between one or more independent variables. RSM can be used to optimize the fermentation medium for the production of Cyclosporin A from the isolate ...
Sunaryanto, R. (Rofiq)
core   +4 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Optimization of Pectinase Production from Bacillus velezensis Isolated from Agro-waste using Response Surface Methodology

Journal of Pure and Applied Microbiology
Pectinases are important enzymes with significant applications in the industrial processing of juice clarification, oil and tea extraction, and paper manufacturing.
Lakshmi Suresh Kottilingal, Sivagurunathan Paramasivam, Sowndarya Sivaprakasam, Chakrappully Radhakrishnan Meera, Uma Chinnaiyan   +4 more
doaj   +1 more source

Response surface analysis on the effect of temperature and pH on Growth and proteolytic activity of thermophilic Bacillus sp

Brazilian Archives of Biology and Technology, 2010
Proteolytic activity and cell biomass of thermophilic Bacillus sp. strain were evaluated at various levels of initial pH and temperature by applying response surface methodology.
Krystyna Gorlach-Lira, Maria Lourdes Vieira Pedroza, Aleksandra Burdziej-Pokojska, Henryk Rozycki, Hanna Dahm   +4 more
doaj   +1 more source

Response Surface Methodology for Optimizing Hyper Parameters [PDF]

The performance of an algorithm often largely depends on some hyper parameter which should be optimized before its usage. Since most conventional optimization methods suffer from some drawbacks, we developed an alternative way to find the best hyper ...
Czogiel, Irina, Luebke, Karsten, Weihs, Claus   +2 more
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