Results 61 to 70 of about 12,593,396 (297)
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
The possibilities of wheat roller milling optimization using the response surface methodology [PDF]
Roller mills are one of the most frequently used grinding machines especially for cereal milling. Magnitude and type of the forces acting on particle depend on the set of roll parameters.
Fišteš Aleksandar +3 more
doaj +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Yeasts have a very high content of protein; therefore, they could be used as an easy source of protein. [...]
Otilia-Gabriela Bărbieru +4 more
doaj +1 more source
Future directions in response surface methodology for simulation [PDF]
As a tool for gradient estimation and sensitivity analysis in discrete simulation, response surface methodology possesses noteworthy advantages in comparison to some of the more recently developed techniques. This paper surveys future directions for research, development, and application of response surface methodology in discrete simulation.
openaire +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Black Box Simulation Optimization: Generalized Response Surface Methodology. [PDF]
The thesis consists of three papers in the area of Response Surface Methodology (RSM). The first paper deals with optimization problems with a single random objective.
Angun, M.E.
core
THE INFLUENCES OF NATURAL GAS IMPURITIES TO THE SURFACE TENSION OF BLENDED PIPERAZINE-N-METHYLDIETHANOLAMINE (MDEA) SOLUTION [PDF]
This study focuses on the effect of impurities in the natural gas stream on the characteristic of surface tension in the blended piperazine and MDEA solution.
Ismail, Ahmad Fauzi, Ratman, Iwan
core +1 more source

