Results 61 to 70 of about 1,638,463 (351)

Chemically synthesized biofuels from agricultural waste: Optimization operating parameters with surface response methodology (CCD)

open access: yesMethodsX, 2017
Bioethanol is one of the most important alternative renewable energy sources that substitute the fossil fuels. Sugarcane bagasse has a content of cellulose and hemicelluloses, which make it suitable as fermentation substrate when hydrolyzed.
Tesfay Berhe, Omprakash Sahu
doaj   +1 more source

Modeling of Wave Propagation in Inhomogeneous Media [PDF]

open access: yes, 2005
We present a methodology providing a new perspective on modeling and inversion of wave propagation satisfying time-reversal invariance and reciprocity in generally inhomogeneous media.
Curtis, Andrew   +2 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Optimisation of Ultrasonic Conditions as an Advanced Extraction Technique for Recovery of Phenolic Compounds and Antioxidant Activity from Macadamia (Macadamia tetraphylla) Skin Waste

open access: yesTechnologies, 2015
Thousands of tons of macadamia skin waste are generated annually with very limited utilisation of this extensive by-product. The aim of this study was to develop optimal ultrasonic extraction conditions for maximized recovery of phenolic compounds and ...
Adriana Dailey, Quan V. Vuong
doaj   +1 more source

Optimization of β-cyclodextrin-based extraction of antioxidant and anti-browning activities from thyme leaves by response surface methodology [PDF]

open access: yes, 2018
Thyme (Thymus vulgaris) has been demonstrated to extend the shelf-life of food products, being also a potential source of bioactive compounds. The aim of this research was to optimize the ultrasound assisted extraction employing β-cyclodextrin aqueous ...
Buera, Maria del Pilar   +4 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Optimization of the PDMS/biochar nanocomposite membranes using the response surface methodology

open access: yesScience and Engineering of Composite Materials, 2018
To improve the separation performance of the polydimethylsiloxane (PDMS)/bark biochar (BB) nanocomposite membranes used for alcohol/water separation, the preparation conditions of these composite membranes were analyzed and optimized.
Lan Yongqiang, Yan Ning, Wang Weihong
doaj   +1 more source

Otimização das condições de extração de saponinas em Ampelozizyphus amazonicus usando planejamento experimental e metodologia de superfície de resposta

open access: yesQuímica Nova, 2011
This works describes the use of experimental design and surface response methodology for optimization of saponin extraction from Ampelozizyphus amazonicus.
Fabiane M dos Santos   +5 more
doaj   +1 more source

Optimization, preparation and characterization of rutin-quercetin dual drug loaded keratin nanoparticles for biological applications [PDF]

open access: yesNanomedicine Journal, 2016
Objective(s): Response surface methodology (RSM) by central composite design (CCD) was applied to statistically optimize the preparation of Rutin-Quercetin (Ru-Qr) dual drug loaded human hair keratin nanoparticles as well as evaluate the characteristics.
Selvaraj Kunjiappan   +4 more
doaj   +1 more source

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