Optimization of Anthocyanin Extraction from Saffron Petals with Response Surface Methodology [PDF]
, 2016 Optimum extraction conditions of anthocyanins from petals of saffron (Crocus sativus) using acidified ethanol as the solvent were revealed. The investigated factors were solvent to sample ratio (20:1–80:1), ethanol concentration (%), extraction ...
Ghorbani, M. +4 more
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Optimal Machining Parameters for Achieving the Desired Surface Roughness in Turning of Steel
The Journal of Engineering Research, 2012 Due to the widespread use of highly automated machine tools in the metal cutting industry, manufacturing requires highly reliable models and methods for the prediction of output performance in the machining process.
LB Abhang, M Hameedullah
doaj +1 more source
Comparison of fructan yield of foreign cultivars and indigenous landrace of chicory and optimizing its extraction by response surface method (RSM) [PDF]
Pizhūhish va Nuāvarī dar ̒Ulūm va Sanāyi̒-i Ghaz̠āyī, 2016 Chicory plant is known as one of the main sources of industrial and commercial production of inulin. Inulin composition and its functional features depend on various parameters, including genetic characteristics and plant origin, growth environmental ...
Pegah Darjani +6 more
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On some aspects of second order response surface methodology : a thesis presented in partial fulfilment of the requirements for the degree of M. Sc. in Mathematics at Massey University [PDF]
, 1972 A unified development of the theoretical basis of response surface methodology, particularly as it applies to second order response surfaces, is presented.
Thomas, Vernon John
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Generalized Response Surface Methodology: A New Metaheuristic [PDF]
SSRN Electronic Journal, 2006 Generalized Response Surface Methodology (GRSM) is a novel general-purpose metaheuristic based on Box and Wilson.s Response Surface Methodology (RSM).Both GRSM and RSM estimate local gradients to search for the optimal solution.These gradients use local first-order polynomials.GRSM, however, uses these gradients to estimate a better search direction ...
openaire +4 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Antioxidants, 2015 The macadamia is native to Australia and is now grown commercially around the world. Macadamia skin, known as waste, has been generated abundantly, but this ample source has had limited uses as a byproduct.
Adriana Dailey, Quan V. Vuong
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A study into compression ring dynamics using response surface methodology [PDF]
, 2015 For decades the operational dynamics of the compression ring during operation, have been subject to debate. A complex computer simulation, using Design Of Experiments (DOE) methodology, was developed to study the effect of the compression ring rotation ...
Dickinson, Matthew
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