Results 41 to 50 of about 12,593,396 (297)

Response surface methodology and its application in simulation [PDF]

Proceedings of the 25th conference on Winter simulation - WSC '93, 1993
The contents of this paper reflect a portion of the conference tutorial on the application of response surface methodology to simulation. In this paper we will present an outline of the methodology and give a simple example of its application to a two variable optimization problem.
S.J. Hood, P.D. Welch
openaire   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Optimal Machining Parameters for Achieving the Desired Surface Roughness in Turning of Steel

The Journal of Engineering Research, 2012
Due to the widespread use of highly automated machine tools in the metal cutting industry, manufacturing requires highly reliable models and methods for the prediction of output performance in the machining process.
LB Abhang, M Hameedullah
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Generalized Response Surface Methodology: A New Metaheuristic [PDF]

SSRN Electronic Journal, 2006
Generalized Response Surface Methodology (GRSM) is a novel general-purpose metaheuristic based on Box and Wilson.s Response Surface Methodology (RSM).Both GRSM and RSM estimate local gradients to search for the optimal solution.These gradients use local first-order polynomials.GRSM, however, uses these gradients to estimate a better search direction ...
openaire   +4 more sources

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

A new adaptive response surface method for reliability analysis [PDF]

, 2013
Response surface method is a convenient tool to assess reliability for a wide range of structural mechanical problems. More specifically, adaptive schemes which consist in iteratively refine the experimental design close to the limit state have received ...
Salaün, Michel, Petitjean, Frank, Roussouly, Nicolas   +2 more
core   +1 more source

Extraction and Functional Properties of Crude Prolamin from Amaranth

Foods
The objective of this study was to evaluate the structural, functional and morphological characterizations of ultrasonic-assisted extraction of crude prolamin from amaranth grain (Amaranthus hypochondriacus L.).
Yujun Dong, Xiaojun Hu, Yajuan Wang, Li He   +3 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Optimisation of fermentation conditions in the production of ethanol from Palmer mango

Semina: Ciências Exatas e Tecnológicas, 2018
The objective of this work is to analyse the production potential and optimize the aqueous pulp extract of Palmer mangoes for the production of ethanol.
Simone de Lima Côrtes, Dionisio Borsato, Marissa Kimura, Ivanira Moreira, Olívio Fernandes Galão, Silvia Borba Costa   +5 more
doaj   +1 more source