Results 41 to 50 of about 13,211,263 (298)

Extraction and Functional Properties of Crude Prolamin from Amaranth

Foods
The objective of this study was to evaluate the structural, functional and morphological characterizations of ultrasonic-assisted extraction of crude prolamin from amaranth grain (Amaranthus hypochondriacus L.).
Yujun Dong, Xiaojun Hu, Yajuan Wang, Li He   +3 more
doaj   +1 more source

Optimal Machining Parameters for Achieving the Desired Surface Roughness in Turning of Steel

The Journal of Engineering Research, 2012
Due to the widespread use of highly automated machine tools in the metal cutting industry, manufacturing requires highly reliable models and methods for the prediction of output performance in the machining process.
LB Abhang, M Hameedullah
doaj   +1 more source

Using response-surface methodology to detect chaos in ecological time series

, 1993
The performance of Turchin and Taylor's response-surface methodology in characterizing the endogenous dynamics underlying ecological time series is studied for the aphid Phyllaphis fagi. The results are shown to be sensitive to further data from the same
Hanski, I., Perry, J. N., Woiwod, I. P., Woiwod, Ian   +3 more
core   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Response surface methodology and its application in simulation [PDF]

Proceedings of the 25th conference on Winter simulation - WSC '93, 1993
The contents of this paper reflect a portion of the conference tutorial on the application of response surface methodology to simulation. In this paper we will present an outline of the methodology and give a simple example of its application to a two variable optimization problem.
S.J. Hood, P.D. Welch
openaire   +1 more source

RESPONSE SURFACE EXPERIMENTS ON PROCESSES WITH HIGH VARIATION

, 2006
In industries such as food engineering, pharmaceuticals, bioprocessing and agrochemicals the use of biological materials means that, when experiments are being performed, run to run variation is typically higher than in many other engineering ...
Gilmour, Steven G., Trinca, Luzia A. [UNESP], Steven G. Gilmour, Luzia A. Trinca, Trinca, Luzia A.   +4 more
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Coagulation: Determination of key operating parameters by multi-response surface methodology using desirability functions [PDF]

, 2019
The clarification process removes colloidal particles that are suspended in waste water. The efficiency of this process is influenced by a series of inputs or parameters of the coagulation process, of which the most commonly used are initial turbidity ...
González, Eliseo P. Vergara [0000-0002-0083-6401], Gómez, F. S., Lorza, Rubén Lostado [0000-0001-5902-6078], Bobadilla, Marina Corral [0000-0002-6057-7077], García, Rubén Escribano [0000-0003-2612-942X], Lorza, R. L., García, R. E., Fátima Somovilla Gómez, Bobadilla, M. C., Rubén Lostado Lorza, Eliseo P. Vergara González, Gómez, Fátima Somovilla [0000-0002-5286-0243], Vergara González, Eliseo Pablo, Marina Corral Bobadilla, Rubén Escribano García, González, Eliseo P. Vergara, Gómez, Fátima Somovilla, Lorza, Rubén Lostado, 0000-0001-5902-6078, 0000-0002-6057-7077, 0000-0003-2612-942X, Bobadilla, Marina Corral, García, Rubén Escribano   +22 more
core   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source