Results 31 to 40 of about 12,593,396 (297)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
International Journal of Electrochemical Science, 2020 Based on the strongenhancement effect of metoclopramide on the electrochemiluminescencesignal of Ru(bpy)32+ on the platinum electrode, a novelmethod for the sensitive detection of metoclopramide was established.
Fuxiu Yang +5 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Journal of Natural Fibers, 2021 In the last decades, eco-friendly materials are playing an interesting role. Particularly, many studies deal with the use of natural fibers as a replacement to synthetic fibers in the plaster matrix.
Messaouda Boumaaza +2 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Response surface experiments on processes with high variation
, 2006 In industries such as food engineering, pharmaceuticals, bioprocessing and agrochemicals the use of biological materials means that, when experiments are being performed, run to run variation is typically higher than in many other engineering ...
Gilmour, Steven G. +1 more
core +1 more source
Saudi Pharmaceutical JournalAn orally administered bilayer tablet with Tamsulosin (TAM) as the sustained release (SR) and Finasteride (FIN) as immediate release (IR) was manufactured.
Muneeba Akhtar +11 more
doaj +1 more source
Comparison of fructan yield of foreign cultivars and indigenous landrace of chicory and optimizing its extraction by response surface method (RSM) [PDF]
Pizhūhish va Nuāvarī dar ̒Ulūm va Sanāyi̒-i Ghaz̠āyī, 2016 Chicory plant is known as one of the main sources of industrial and commercial production of inulin. Inulin composition and its functional features depend on various parameters, including genetic characteristics and plant origin, growth environmental ...
Pegah Darjani +6 more
doaj +1 more source