Results 51 to 60 of about 1,638,463 (351)
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Multi-objective design of antenna structures using variable-fidelity EM simulations and co-kriging [PDF]
, 2014 A methodology for low-cost multi-objective design of antenna structures is proposed. To reduce the computational effort of the design process the initial Pareto front is obtained by optimizing the response surface approximation (RSA) model obtained from ...
Couckuyt, Ivo +3 more
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
THE OPTIMIZATION OF PRODUCTION ZEOLITE Y CATALYST FROM RHA BY RESPONSE SURFACE METHODOLOGY [PDF]
, 2009 Rice husk is the milling byproduct of rice and is a major waste product of the agriculture industry. Amorphous silica, commonly referred to as rice husk ash, was extracted from rice husk by acid leaching, pyrolysis, and carbon-removing processes.
Anggoro, Didi Dwi, Aprilina, Purbasari
core
Improved Multiple Comparisons With The Best In Response Surface Methodology [PDF]
, 2003 A method to construct simultaneous confidence intervals about the difference in mean responses at the stationary point and at x for all x within a sphere with radius I R is proposed.
Miller, Laura K., Sa, Ping
core +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Optimization of Reaction Conditions in the Production of Gadolinium Diethylenetriamine Pentaacetate-Folate [PDF]
, 2015 A previous study has performed the laboratory-scale synthesis and characterization of Gadolinium Diethylenetriaminepentaacetate-Folate. Some parameters associated with the synthesis have been defined.
Anggraeni, A. +3 more
core
Using response surface methodology to optimize factors in conjoint experiments [PDF]
, 2018 Identifying relevant attributes or variables is the first objective of conjoint analysis in market research. As a result of technological development, today it is common for researchers to use sequential experimental methods for adjusting design factors ...
Esteban Millat, Irene +3 more
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Saudi Pharmaceutical JournalAn orally administered bilayer tablet with Tamsulosin (TAM) as the sustained release (SR) and Finasteride (FIN) as immediate release (IR) was manufactured.
Muneeba Akhtar +11 more
doaj +1 more source