Results 71 to 80 of about 1,638,463 (351)

Effect of flocculation on lipid extraction from Chlorella vulgaris Utex 1803 using response surface methodology [PDF]

, 2019
Microalgae are an attractive source of metabolites, such as lipids, proteins, pigments and carbohydrates, of potential interest to the pharmaceutical, food and energy sectors.
Diaz, Manuel Alejandro Ortegón, Garcia, Janet Bibiana, Gonzalez-Delgado, Angel Dario, Lavecchia, Roberto, Lopez, Nelson Osvaldo Mena, Solano, Andres Fernando Barajas, Zuorro, Antonio   +6 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Optimization of cyclodextrin glycosyltransferase production by response surface methodology approach. [PDF]

, 2008
The aim of the study was to optimized cyclodextrin glycosyltransferase (CGTase) production using local isolated strain MK6 which was identified as Bacillus sp.
Abd Aziz, Suraini, Abdul Karim, Mohamed Ismail, Ai-Noi, Sauvaphap, Hassan, Osman, Mohamed Alitheen, Noorjahan Banu   +4 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Minimizing surface roughness and back wall dross for fiber laser micro-cutting on AISI 316 L tubes using response surface methodology

Materials Research Express
A response surface methodology (RSM) was performed to study the influence of spot overlapping and pulse energy on back wall dross and surface roughness for fiber laser cutting of AISI 316 L stainless steel minitubes.
Erika García-López, Hector Siller, Elisa Vazquez-Lepe, José Guillermo Ramirez-Galindo, Ciro A Rodriguez   +4 more
doaj   +1 more source

Robust Optimization in Simulation: Taguchi and Response Surface Methodology [PDF]

Optimization of simulated systems is tackled by many methods, but most methods assume known environments. This article, however, develops a 'robust' methodology for uncertain environments.
Dellino, G., Kleijnen, J.P.C., Meloni, C.   +2 more
core   +1 more source

A Process Planning Method and Data Format for Achieving Tolerances in Stereolithography [PDF]

, 1998
When building parts in a stereolithography apparatus (SLA), the user is faced with many decis!ons regarding the setting of process variables. To 'achieve a set of tolera~ces as closely as pOSSIble, relationships between part geometry, tolerances, and ...
Lynn, Charity M., Rosen, David W., West, Aaron   +2 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Optimization of Yeast Protein Extraction through a Combined Enzymatic and High-Pressure Homogenization Method

Proceedings, 2020
Yeasts have a very high content of protein; therefore, they could be used as an easy source of protein. [...]
Otilia-Gabriela Bărbieru, Naomi Tritean, Bogdan Trică, Diana Constantinescu-Aruxandei, Florin Oancea   +4 more
doaj   +1 more source