Results 131 to 140 of about 2,244,366 (395)

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

open access: yesFEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu   +6 more
wiley   +1 more source

Response Surface Methodology (RSM) approach to formulate and optimize the bilayer combination tablet of Tamsulosin and Finasteride

open access: yesSaudi Pharmaceutical Journal
An orally administered bilayer tablet with Tamsulosin (TAM) as the sustained release (SR) and Finasteride (FIN) as immediate release (IR) was manufactured.
Muneeba Akhtar   +11 more
doaj  

Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification

open access: yesFEBS Open Bio, EarlyView.
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski   +13 more
wiley   +1 more source

Integrating steepest ascent for the taguchi experiment: A simulation study [PDF]

open access: yes, 2013
Many previous researches conveyed the superiority of Steepest Ascent (SA) method to find the optimal area in Response Surface Methodology (RSM) by shifting the experiment factor level.
Hadiyat, Mochammad Arbi   +1 more
core  

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

open access: yesFEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji   +3 more
wiley   +1 more source

Foam mat drying of tomato pulp

open access: yesBioscience Journal, 2013
The purpose of this study was to optimize the formulation of tomato pulp foam and to evaluate the drying process using the foam mat method at temperatures of 60°C and 80°C.
Regiane Victória de Barros Fernandes   +5 more
doaj  

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

open access: yesFEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa   +13 more
wiley   +1 more source

OPTIMIZATION AND CHARACTERIZATION OF POLYSULFONE MEMBRANES MADE OF ZINC OXIDE, POLYETHYLENE GLYCOL AND EUGENOL AS ADDITIVES [PDF]

open access: yesJournal of Engineering Science and Technology, 2016
The aim of this study to investigate the effect of zinc oxide, polyethylene glycol (PEG) and eugenol on the properties of membranes made of polysulfone (PSf). Polysulfone membranes were prepared via phase inversion method using Nmethyl-2-pyrolidone (NMP)
MUHAMAD ZAINI YUNOS   +4 more
doaj  

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