Results 101 to 110 of about 17,987,828 (337)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Optimización de curvas de crecimiento a través de análisis univariado

Revista Colombiana de Estadística, 2008
En este artículo se propone una metodología de modelamiento conjunto de tratamientos con niveles cuantitativos medidos en el tiempo, a través de la combinación de las metodologías de superficie de respuesta y curvas de crecimiento.
SARA CRISTINA GUERRERO, ÓSCAR ORLANDO MELO   +1 more
doaj  

Modeling synergistic effects by using general Hill-type response surfaces describing drug interactions. [PDF]

Sci Rep, 2022
Schindler M.
europepmc   +1 more source

Comparison of polynomial approximations and artificial neural nets for response surfaces in engineering optimization [PDF]

Engineering optimization problems involve minimizing some function subject to constraints. In areas such as aircraft optimization, the constraint equations may be from numerous disciplines such as transfer of information between these disciplines and the
Carpenter, William C.
core   +1 more source

Electromagnetic analysis of arbitrarily shaped pinched carpets

, 2010
We derive the expressions for the anisotropic heterogeneous tensors of permittivity and perme- ability associated with two-dimensional and three-dimensional carpets of an arbitrary shape. In the former case, we map a segment onto smooth curves whereas in
A. Greenleaf, A. J. Ward, Guillaume Dupont, R. V. Kohn, Stefan Enoch, Sébastien Guenneau, W. Cai   +6 more
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

On the effect of preferential sampling in spatial prediction

, 2012
The choice of the sampling locations in a spatial network is often guided by practical demands. In particular, many locations are preferentially chosen to capture high values of a response, for example, air pollution levels in environmental monitoring ...
Banerjee, Banerjee, Chakraborty, Cocchi, Cressie, Dawid, Diggle, Diggle, Hooten, Illian, Latimer, Lee, Lewis, Müller, Nychka, Pati, Pilz, Sahu, Sahu, Sheppard, Theobald, Xia   +21 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Tuning a fuzzy controller using quadratic response surfaces [PDF]

Response surface methodology, an alternative method to traditional tuning of a fuzzy controller, is described. An example based on a simulated inverted pendulum 'plant' shows that with (only) 15 trial runs, the controller can be calibrated using a ...
Schott, Brian, Whalen, Thomas
core   +1 more source

How Voltage Drops are Manifested by Lithium Ion Configurations at Interfaces and in Thin Films on Battery Electrodes

, 2015
Battery electrode surfaces are generally coated with electronically insulating solid films of thickness 1-50 nm. Both electrons and Li+ can move at the electrode-surface film interface in response to the voltage, which adds complexity to the "electric ...
Leenheer, Andrew, Leung, Kevin
core   +2 more sources