Results 81 to 90 of about 17,987,828 (337)

Isogeometric analysis applied to frictionless large deformation elastoplastic contact [PDF]

open access: yes, 2013
This paper focuses on the application of isogeometric analysis to model frictionless large deformation contact between deformable bodies and rigid surfaces that may be represented by analytical functions. The contact constraints are satisfied exactly with
Kvamsdal, Trond   +3 more
core  

Group-Theoretical Analysis of Second Harmonic Generation at (110) and (111) Surfaces of Antiferromagnets

open access: yes, 1999
Extending our previous work we classify the nonlinear magneto-optical response at low index surfaces of fcc antiferromagnets, such as NiO. Antiferromagnetic bilayers are discussed here as models for the termination of bulk antiferromagnets.Comment: 7 ...
Hübner, W., Trzeciecki, M.
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Proteomic Response of Pseudomonas aeruginosa PAO1 Adhering to Solid Surfaces

open access: yesFrontiers in Microbiology, 2017
Pseudomonas aeruginosa is a pathogenic micro-organism responsible for many hospital-acquired infections. It is able to adhere to solid surfaces and develop an immobilized community or so-called biofilm.
Morgan Guilbaud   +9 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Analysis of the Cellular Response to Different Dental Implant Surfaces: An In vitro Study

open access: yesJournal of Pharmacy and Bioallied Sciences
Background: Dental implant surfaces play a crucial role in determining the success of osseointegration and long-term stability. Understanding the cellular response to various implant surfaces is essential for optimizing implant design and clinical ...
Mohammed G. Sghaireen   +5 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Efecto de la presión de vacío, sólidos solubles totales y tiempo de procesamiento sobre la deshidratación osmótica de rebanadas de melón Effect of the pressure of vacuum, total soluble solids and processing time on the osmotic dehydration of slices of melon

open access: yesBioagro, 2010
Se estudió la deshidratación osmótica de rebanadas de melón (Cucumis melo L.) como alternativa para la obtención de productos secos con características similares a los frescos, y que demanden menos energía para su estabilización, almacenamiento y ...
Luis Chaparro   +4 more
doaj  

Spectral Response Surfaces and the Ringing Response of Offshore Structures [PDF]

open access: yes, 2008
A method, called spectral response surface method, is proposed for the study of the ringing phenomenon of offshorestructures. Newman’s results for diffraction force on a column were reformulated in terms of the frequency componentsof the ocean ...
Suastika, I. K. (I)
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

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