Results 81 to 90 of about 6,785,013 (298)

Fitting functional response surfaces to data: a best practice guide

Ecosphere, 2020
Describing how resource consumption rates depend on resource density, conventionally termed “functional responses,” is crucial to understanding the population dynamics of trophically interacting organisms.
Wojciech Uszko, Sebastian Diehl, Jonas Wickman   +2 more
doaj   +1 more source

Nanometer scale titanium surface texturing are detected by signaling pathways involving transient FAK and Src activations. [PDF]

PLoS ONE, 2014
BACKGROUND:It is known that physico/chemical alterations on biomaterial surfaces have the capability to modulate cellular behavior, affecting early tissue repair.
Willian F Zambuzzi, Estevam A Bonfante, Ryo Jimbo, Mariko Hayashi, Martin Andersson, Gutemberg Alves, Esther R Takamori, Paulo J Beltrão, Paulo G Coelho, José M Granjeiro   +9 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Efecto de la presión de vacío, sólidos solubles totales y tiempo de procesamiento sobre la deshidratación osmótica de rebanadas de melón Effect of the pressure of vacuum, total soluble solids and processing time on the osmotic dehydration of slices of melon

Bioagro, 2010
Se estudió la deshidratación osmótica de rebanadas de melón (Cucumis melo L.) como alternativa para la obtención de productos secos con características similares a los frescos, y que demanden menos energía para su estabilización, almacenamiento y ...
Luis Chaparro, Naudy Soto, Tonny García, Julio Gutiérrez, Jhonny Palmero   +4 more
doaj  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Grouping of tooth surfaces by susceptibility to caries: a study in 5-16 year-old children [PDF]

, 2004
Background The decline in caries has slowed and this may be indicative of variation in the susceptibility of differing teeth to caries. This study tests the hypothesis that in children, there are groups of tooth sites that exhibit differences in caries ...
Sheiham, A, Batchelor Paul A, Sheiham Aubrey, Aubrey Sheiham, Batchelor, P, Paul A Batchelor   +5 more
core   +2 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Analysis of the Cellular Response to Different Dental Implant Surfaces: An In vitro Study

Journal of Pharmacy and Bioallied Sciences
Background: Dental implant surfaces play a crucial role in determining the success of osseointegration and long-term stability. Understanding the cellular response to various implant surfaces is essential for optimizing implant design and clinical ...
Mohammed G. Sghaireen, Mohammad Raji Alrwuili, Nasser Attallah Alenzi, Mohammed Ahmed Aljabab, Rakhi Issrani, Mohammad Khursheed Alam   +5 more
doaj   +1 more source

Proteomic Response of Pseudomonas aeruginosa PAO1 Adhering to Solid Surfaces

Frontiers in Microbiology, 2017
Pseudomonas aeruginosa is a pathogenic micro-organism responsible for many hospital-acquired infections. It is able to adhere to solid surfaces and develop an immobilized community or so-called biofilm.
Morgan Guilbaud, Jérôme Bruzaud, Emeline Bouffartigues, Nicole Orange, Alain Guillot, Anne Aubert-Frambourg, Véronique Monnet, Jean-Marie Herry, Sylvie Chevalier, Marie-Noëlle Bellon-Fontaine   +9 more
doaj   +1 more source