Results 191 to 200 of about 36,694,375 (388)

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Evaluation of AI-enhanced tele-ECG response time and diagnosis in acute chest pain patients. [PDF]

open access: yesFront Cardiovasc Med
Accorsi TAD   +7 more
europepmc   +1 more source

Real-time lava flow forecasting during the 2022 Mauna Loa eruption response [PDF]

open access: hybrid
David Hyman   +13 more
openalex   +1 more source

LNIRT: LogNormal Response Time Item Response Theory Models [PDF]

open access: gold, 2016
Jean-Paul Fox, Konrad Klotzke, Rinke Klein Entink
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Response time of global deltas to changes in fluvial sediment supply. [PDF]

open access: yesNat Commun
Wang J   +4 more
europepmc   +1 more source

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