Results 101 to 110 of about 2,007,077 (278)
Responsibilities and rights of spiritual children
Волинський благовісник, 2016 The responsibilities and rights of spiritual children in relation to their spiritual mentors based on quotes of Bible, statements of monk Simeon Athos, answers of Venerable Varsonofy Great and John Prophet the questions of pupils are defined.
Olesia Totska
doaj
Entangled harms: A reparative approach to climate justice
Leiden Journal of International LawTransnational climate litigation has become a strategic tool to press state and non-state actors into action. An analysis of international and domestic cases shows how rights and obligations are being materially, subjectively, spatially and temporally ...
Marie Petersmann
doaj +1 more source
The role and responsibilities of a midwifery mentor [PDF]
, 2014 Midwifery Basics: Mentorship 1 Mentorship of student midwives in clinical practice is an important part of the role of a qualified and experienced midwife (Steele 2009).
Jarvis, Yvonne, Marshall, Joyce
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Le design des dispositifs d’automesure du sommeil
Tic & SociétéThis article focuses on a review of U.S. patents dedicated to sleep monitoring and management. It looks specifically at digital inventions that enable the self-monitoring of sleep time and quality through the use of connected devices (quantified sleep ...
Cédric Calvignac
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Ensuring Linguistic Access in Health Care Settings: An Overview of Current Legal Rights and Responsibilities [PDF]
, 2003 Focuses on the language access responsibilities of healthcare and coverage providers pursuant to federal and state laws and ...
Jane Perkins
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source