Results 101 to 110 of about 5,192,011 (281)
Syria and the Responsibility to Protect [PDF]
, 2020 The civilian protection agenda has tried to fill critical gaps in the existing normative architecture through the Responsibility to Protect (R2P) and protection of civilians (POC) as sibling norms.1 Despite these two valuable additions to the repertoire ...
Thakur, Ramesh
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Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Parental responsibility: A legal perspective [PDF]
, 2007 Parental responsibility is often discussed in relation to the care and treatment of children–but what is parental responsibility? Who has it and what does it allow the person who has it to do?
Cornock, Marc
core +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Resources, 2017 Regional planning approaches to mining infrastructure aim to reduce the conflict associated with mining operations and existing land uses, such as urban areas and biodiversity conservation, as well as the cumulative impacts that occur offsite.
Alex M. Lechner +8 more
doaj +1 more source
Grounding Responsibility in Appropriate Blame [PDF]
, 2017 When confronted with the question of why it is appropriate to morally blame a person for some bad action, it may seem plausible to reply that she is morally responsible for it.
Menges, Leonhard
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Corporate social responsibility and banks [PDF]
, 2009 Article discussing ethical issues and matters of social responsibility surrounding turmoil in the capital markets, bank failures and government intervention. Article by Charles Chatterjee (Global Policy Institute, London Metropolitan University) and Anna
Chatterjee, Charles, Lefcovitch, Anna
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