Results 61 to 70 of about 2,478,118 (289)

Effectiveness of an educational asthma management program (CuidAR): the protocol for a cluster-randomized trial in the Brazilian primary healthcare setting

Trials
Background Asthma is one of the most prevalent chronic pulmonary diseases, affecting approximately 20 million Brazilian people. Most patients with asthma in Brazil present with uncontrolled disease, leading to high morbidity and mortality rates ...
Ana Paula Tussi Leite, Géssica Luana Antunes, Amanda Paz Santos, Ingrid Rodrigues Fernandes, Lauren Sezerá Costa, Tássia Rolim Camargo, Camila Bonalume Dall’ Aqua, Fernando Rovedder Boita, Alessandra da Silva Mota, Mariana Motta Dias da Silva, Mariah Prata Soldi Passos Taube, Bruna Silveira da Rosa, Marcus Herbert Jones, Álvaro A. Cruz, Frederico Friedrich, Paulo M. Pitrez   +15 more
doaj   +1 more source

National Commission on Fiscal Responsibility and Reform

, 2010
This website contains information about the National Commission on Fiscal Responsibility and Reform and its working groups. It includes a description of the commission's charter, by-laws, and general information, as well as a list of committee members ...
United States. National Commission on Fiscal Responsibility and Reform.
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The Determinants of Decent Work in Moroccan Cooperatives and Implications for Public Action: Toward Public Action through Determinants

Economies
In a context marked by growing inequalities and sustainable development challenges, Moroccan cooperatives represent an opportunity to reconcile economic objectives with social issues. Rooted in principles of solidarity and democratic participation, these
Badr El Azhari, Mohammed Bougroum, Lahcen Ait Daoud, Houmam Lotfi   +3 more
doaj   +1 more source

Telemedicine outcome of mechanically ventilated children in Brazilian pediatric intensive care units [PDF]

Clinical and Experimental Pediatrics
Background Pediatric intensive care units (PICUs) have undergone significant evolution, resulting in a reduction in patient morbidity and mortality rates.
Aristóteles de Almeida Pires, Luciano Remião Guerra, João Ronaldo Mafalda Krauzer, Luciane Gomes da Cunha, Mariana Motta Dias da Silva, Vanessa Cristina Jacovas, Hilda Maria Rodrigues Moleda Constant, Taís de Campos Moreira, Paulo Márcio Pitrez, Felipe Cezar Cabral   +9 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

New Paradigm of Lean Six Sigma in the 4th Industrial Revolution Era

Kvalita Inovácia Prosperita, 2020
Purpose: In early 2000s Six Sigma and Lean were combined into Lean Six Sigma (LSS), which has been one of the major strategic quality initiatives all over the world.
Sung Hyun Park, Su Mi Dahlgaard-Park, Dong-Chun Kim   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Integrating Industrial Ecology Thinking into the Management of Mining Waste

Resources, 2015
Mining legacies are often dominated by large waste facilities and their associated environmental impacts. The most serious environmental problem associated with mine waste is heavy metals and acid leakage through a phenomenon called acid mine drainage ...
Éléonore Lèbre, Glen Corder
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source