Results 71 to 80 of about 5,256,565 (278)

An Essay towards an Epistemology of Responsibility: A Probabilistic Approach [PDF]

open access: yes, 2016
This paper tries to develop an epistemological analysis on the notion of responsibility. After pointing out a peculiar kind of uncertainties concerning the notion of responsibility, I focus upon the issue of criminal responsibility, taking the case of ...
Ichinose, Masaki
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Assessing self-responsibility in employability competencies development among Australian engineering students: introductory report [PDF]

open access: yes, 2016
Self-responsibility study initially outlined the importance of ‘self-directed Adult learning’ either as the method or the outcome of education.
Ferris, T. L. J., Lazarus, D.
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Ranking Agents of Justice: When Should the Corporation Act? [PDF]

open access: yes, 2018
Theorists have argued that under certain background conditions the commercial, for-profit corporation might bear responsibility to act to advance justice.
Williams, Athol
core  

Responsibility and the modern corporation [PDF]

open access: yes, 2018
Corporate governance crises as well as human rights issues in global value chains have pushed notions of Corporate Social Responsibility (CSR), Corporate Citizenship (CC), Triple P (People, Planet, Profit) and sustainable development onto the agenda of ...
Veldman, J.
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Robots, Autonomy, and Responsibility [PDF]

open access: yes, 2016
We study whether robots can satisfy the conditions for agents fit to be held responsible in a normative sense, with a focus on autonomy and self-control.
Hakli, Raul, Mäkelä, Pekka
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Peak flow meter is a sensitive test for assessing airflow limitation in patients with respiratory symptoms suggestive of asthma in primary health care in Brazil

open access: yesBMC Primary Care
Background The peak flow meter is considered a complementary tool to spirometry for monitoring obstructive lung diseases. In many countries, spirometry is not easily accessible for diagnosing asthma in primary care.
Ana Paula Tussi Leite   +12 more
doaj   +1 more source

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