Results 91 to 100 of about 1,419,624 (297)

Responsibility to Protect and the Challenges of Displaced Men in Nigeria

open access: yesJournal of Danubian Studies and Research, 2020
This study addresses responsibility to protect and the challenges of displaced men in Nigeria. It argues that the challenges facing displaced people in Nigeria as a result of Boko Haram, natural and man-made disasters, as well as the Hausa-Fulani ...
Ejiroghene Augustine Oghuvbu   +1 more
doaj  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

From Human Security to the Responsibility to Protect: The Co-option of Dissent? [PDF]

open access: yes, 2015
In this article I argue that the Responsibility to Protect (R2P) has sanitized much of the revolutionary potential of human security. While R2P has not subsumed human security — the latter arguably involves a broader array of issues and themes which ...
Hehir, A., Hehir, A.
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

RESPONSIBILITY TO PROTECT AND HUMAN SECURITY IN UN’S INVOLVEMENT IN LIBYA

open access: yesStudia Universitatis Babeş-Bolyai. Studia Europaea, 2019
The article discusses the responsibility to protect (RtoP) and the shift from a right for humanitarian intervention towards a global responsibility to protect civilians, as exemplified by the wording of Resolutions 1970 and 1973.
Laura-Maria HERȚA
doaj   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Applying the Responsibility to Protect to the Arab Spring [PDF]

open access: yes
The doctrine of the responsibility to protect, since its inception in the ICISS report of 2001, has been the subject of considerable discussion.
Wilson, G
core  

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