Results 71 to 80 of about 200,089 (297)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Ethical Implications of AI‐Driven Chatbots in Domestic Violence Support

open access: yesSocial Inclusion
Our study explored the opportunities, challenges, and ethical considerations of using artificial intelligence (AI)‐driven chatbots in domestic violence (DV) support. DV is a serious public health and social problem. Identifying it as early as possible is
Hanna Mielismäki, Marita Husso
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Thinking responsibly about responsible AI and ‘the dark side’ of AI [PDF]

open access: yesEuropean Journal of Information Systems, 2022
Patrick Mikalef   +3 more
openaire   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Ethics-Centered Approach to the Development and Application of Artificial Intelligence in Agriculture [PDF]

open access: yesInternational Journal of Ethics and Society
Introduction: Artificial intelligence (AI) is revolutionizing agriculture by enhancing precision farming, resource management, and productivity. However, the extensive use of AI raises significant ethical challenges related to privacy protection, data ...
Ahmad Abedi Sarvestani
doaj  

GeoAI for Science and the Science of GeoAI

open access: yesJournal of Spatial Information Science
This paper reviews trends in GeoAI research and discusses cutting-edge advances in GeoAI and its roles in accelerating environmental and social sciences.
Wenwen Li   +6 more
doaj   +1 more source

Panel: 'Responsible AI of the Future' and Signing ceremony

open access: yes, 2018
Discussion on the topic "Critical Uncertainties for the Development of Responsible AI of the Future" with an excellent expert panel at the ICT ...
Müller, Christoph   +5 more
core  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

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