Results 51 to 60 of about 200,089 (297)
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Chord Types and Figuration: A Bayesian Learning Model of Extended Chord Profiles
Music & ScienceMaking sense of a musical excerpt is an acquired skill that depends on previous musical experience. Having acquired familiarity with different types of chords, a listener can distinguish tones in a musical texture that outline these chords (i.e., chord ...
Christoph Finkensiep +3 more
doaj +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
The role and challenges of education for responsible AI
London Review of Education, 2021 Artificial intelligence (AI) is impacting education in many different ways. From virtual assistants for personalized education, to student or teacher tracking systems, the potential benefits of AI for education often come with a discussion of its ...
doaj +2 more sources
Navigating ethical challenges in generative AI-enhanced research: The ETHICAL framework for responsible generative AI use [PDF]
The rapid adoption of generative artificial intelligence (GenAI) in research presents both opportunities and ethical challenges that should be carefully navigated.
Eacersall, Douglas +15 more
core +1 more source
A responsible AI framework: pipeline contextualisation
, 2022 International audienceAbstract Incorporating ethics and values within the life cycle of an AI asset means securing its development, deployment, use, and decommission under these perspectives.
Thevenin, Simon +3 more
core +1 more source
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Responsible AI for labour market equality (BIAS)
, 2022 The BIAS case study describes the aims and objectives of the ‘BIAS: Responsible AI for labour market equality’ project, the research process, and the lessons learned at the mid-way point of the project.
Al-Ani, Jabir Alshehabi +11 more
core +1 more source