Results 51 to 60 of about 3,421,628 (295)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Fostering responsible anticipation in engineering ethics education: how a multi-disciplinary enrichment of the responsible innovation framework can help

It is crucial for engineers to anticipate the socio-ethical impacts of emerging technologies. Such acts of anticipation are thoroughly normative and should be cultivated in engineering ethics education.
Janna van Grunsven, Taylor Stone, Lavinia Marin   +2 more
semanticscholar   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Establishing circularity: development and validation of the circular work value scale (CWVS)

Frontiers in Psychology
ObjectivesAddressing the lack of German-language instruments, this study aims to develop a questionnaire that enables the measurement of work values. According to the theory of basic human values (Schwartz, 1992), a culturally fitting questionnaire is ...
Jannick Schneider, Jannick Schneider, Clemens Striebing, Katharina Hochfeld, Timo Lorenz   +4 more
doaj   +1 more source

Responsible innovation in emerging markets’ SMEs: The role of alliance learning and absorptive capacity

Asia Pacific Journal of Management, 2022
This paper presents an examination of the role played by alliance learning in enabling emerging market small and medium-sized enterprises (SMEs) to develop responsible innovation.
N. Zahoor, Huda Khan, Zaheer Khan, Pervaiz Akhtar   +3 more
semanticscholar   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Foresighting Australian digital agricultural futures: Applying responsible innovation thinking to anticipate research and development impact under different scenarios

, 2021
CONTEXT Public and private research institutions are grappling with the challenges and opportunities of embedding dimensions of responsible innovation within their research and development programs, including those seeking to transform agricultural ...
A. Fleming, E. Jakku, S. Fielke, Bruce V. Taylor, J. Lacey, A. Terhorst, Cara A. Stitzlein   +6 more
semanticscholar   +1 more source

Extended Reality in Higher Education, a Responsible Innovation Approach for Generation Y and Generation Z

Sustainability, 2021
This study aims to provide a comprehensive overview of the XR challenges, opportunities, and future trends that will impact higher educational institutions.
Valentin Kuleto, M. P., M. Stănescu, M. Ranković, N. Šević, D. Păun, S. Teodorescu   +6 more
semanticscholar   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Transparency in the secondary use of health data: assessing the status quo of guidance and best practices

Royal Society Open Science
We evaluated what guidance exists in the literature to improve the transparency of studies that make secondary use of health data. To find peer-reviewed papers, we searched PubMed and Google Scholar.
Olmo R. van den Akker, Robert T. Thibault, John P. A. Ioannidis, Susanne G. Schorr, Daniel Strech   +4 more
doaj   +1 more source