Results 51 to 60 of about 1,402,994 (298)

Responsible Innovation for Decent Nonliberal Peoples: A Dilemma? [PDF]

, 2016
It is hard to disagree with the idea of responsible innovation (henceforth, RI), as it enables policy-makers, scientists, technology developers, and the public to better understand and respond to the social, ethical, and policy challenges raised by new ...
Wong, Pak-Hang
core  

Responsible design : a conceptual look at interdependent design–use dynamics [PDF]

, 2011
This article investigates the conceptual foundations of technological innovation and development projects that aim to bring ethical and social issues into the design stage.
Kiran, A.H.
core   +4 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Establishing circularity: development and validation of the circular work value scale (CWVS)

Frontiers in Psychology
ObjectivesAddressing the lack of German-language instruments, this study aims to develop a questionnaire that enables the measurement of work values. According to the theory of basic human values (Schwartz, 1992), a culturally fitting questionnaire is ...
Jannick Schneider, Jannick Schneider, Clemens Striebing, Katharina Hochfeld, Timo Lorenz   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Agriculture 4.0: broadening responsible innovation in an era of smart farming [PDF]

, 2018
Agriculture is undergoing a technology revolution supported by policy-makers around the world. While smart technologies will play an important role in achieving enhanced productivity and greater eco-efficiency, critics have suggested that a consideration
Asveld, Bear, Blok, Bronson, Burall, Carbonell, Carolan, Carson, Chilvers, Chilvers, Chilvers, Dicks, Dicks, Driessen, Eastwood, Fennimore, Firbank, Frankelius, Gadanakis, Goodman, Gunton, Gupta, Hajer, Hartley, Higgins, Holloway, Holloway, Jasanoff, Klerkx, Leach, Lejon, Long, Lottes, López, Macnaghten, Macnaghten, Macnaghten, Mahon, Marres, Nordmann, Pretty, Purwins, Rogers, Rose, Rose, Rose, Rose, Satterthwaite, Sen, Smith, Stilgoe, Struik, Tambo, Waters-Bayer, Whitfield, Wolf, Wolfert, Woolston   +57 more
core   +3 more sources

Responsible research and innovation

This chapter summarises the history and significance of the concept of responsible research and innovation (RRI) in Europe and the emergence of a linked community of practice in research and policy arenas.
Woolley, Richard, Otero-Hermida, Paula, Monsonís-Payá, Irene, Wicher, Magdalena   +3 more
openaire   +2 more sources

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Inside innovation. Year 2. An evaluation of the second year of delivery of a project promoting innovative thinking amongst Prison Service staff [PDF]

, 2007
The Inside Innovation programme is the result of a partnership between Media For Development (MFD) and UnLtd. The Inside Innovation programme forms part of MFD’s multi-award winning Inside Job initiative that operates within the criminal justice system ...
Davidson, J., Wilkinson, Katherine
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