Results 151 to 160 of about 1,354,140 (303)

Balancing economic rationality and social responsibility under resource constraints: findings on doctors’ knowledge and timing in medical device innovation

Journal of Responsible Innovation
Resource constraints often hinder companies from balancing economic goals with Responsible Research and Innovation (RRI). In the medical device sector, doctors are critical stakeholders in addressing this challenge, as they integrate patient, clinical ...
Masaya Onuma, Tatsuya Kubota, Atsushi Tsumita   +2 more
doaj   +1 more source

Children in Need of Medical Innovation [PDF]

As the innovation process of pharmaceuticals is a long, risky and very costly business, economists typically emphasise lack of profit incentives and small market size as the most important obstacles to child-related innovative activity.
Entorf, Horst, Fegert, Jörg, Kölch, Michael   +2 more
core  

Validation of a Genetic Risk Score Combined With Clinical Variables for Predicting Pulmonary Fibrosis in Early Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective Pulmonary fibrosis (PF) is a severe extra‐articular manifestation of rheumatoid arthritis (RA). This study aimed to externally validate a genetic risk score (GRS) and a combined risk score (CRS) for predicting the risk of RA‐associated PF in an independent cohort of patients with early RA.
Mikael Brink, Austin Wheeler, Bryant R. England, Solbritt Rantapää‐Dahlqvist   +3 more
wiley   +1 more source

Performance Characteristics of Anti–Collagen II Antibodies in Relapsing Polychondritis and Related Diseases: Prospective Analysis, Systematic Review, and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Relapsing polychondritis (RP) is a rare disease defined by recurrent cartilaginous inflammation. Anti–collagen II (Col2) antibodies have been proposed as a diagnostic biomarker for RP, but their performance characteristics are not well defined.
Karyssa Stonick, Marcela A. Ferrada, Alice Fike, Kaitlin A. Quinn, Benjamin A. Turturice, Casey Stein, Peter C Grayson   +6 more
wiley   +1 more source

Governance of research consortia: challenges of implementing Responsible Research and Innovation within Europe. [PDF]

Life Sci Soc Policy, 2020
Morrison M, Mourby M, Gowans H, Coy S, Kaye J.   +4 more
europepmc   +1 more source

Capturing mink and data : Interacting with a small and dispersed environmental initiative over the introduction of digital innovation [PDF]

, 2013
This case study was carried out by Koen Arts1, Gemma Webster1, Nirwan Sharma1, Yolanda Melero2, Chris Mellish1, Xavier Lambin2 and René van der Wal1. We thank two anonymous reviewers for their suggestions, and Chris Horrill from SMI for his very helpful ...
Arts, Koen Antonius Johannes, Lambin, Xavier, Melero Cavero, Yolanda, Mellish, Christopher Stuart, Sharma, Nirwan, Van Der Wal, Rene, Webster, Gemma   +6 more
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Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) Network investigators   +14 more
wiley   +1 more source

Registration and reporting of clinical trials affiliated with California universities and with primary completion date from 2014 to 2017

Trials
Background Public information on US clinical trials is shared through the ClinicalTrials.gov registry. This study’s goal was to determine prospective registration, results reporting, trial registration number reporting, and publication accessibility ...
Mario Malički, Vladislav Nachev, Susanne Wieschowski, Nicole Hildebrand, Stefanie Gestrich, Samruddhi Yerunkar, Emmanuel Zavalis, Benjamin Gregory Carlisle, Delwen L. Franzen, Maia Salholz-Hillel, Steven N. Goodman, Daniel Strech   +11 more
doaj   +1 more source

Role of Prednisone and 25‐Hydroxyvitamin D on Bone Mineral Density and Osteoporosis in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective We evaluated the role of 25‐hydroxyvitamin D (25[OH]D), prednisone, and other risk factors for bone mineral density (BMD) loss and osteoporosis in systemic lupus erythematosus (SLE). Methods We calculated the association between 25(OH)D levels and other potential risk factors and BMD measures (spine T scores) and osteoporosis (defined as a T ...
Nima Madanchi, Andrea Fava, Daniel W. Goldman, Laurence S. Magder, Michelle Petri   +4 more
wiley   +1 more source

Globalisation of Knowledge Production and Regional Innovation Policy: Supporting Specialized Hubs in the Bangalore Software Industry [PDF]

This paper is concerned with the changing role of regional innovation systems and regional policies in supporting the transition of indigenous firms in developing countries from competing on low costs towards becoming knowledge providers in global value ...
Chaminade, Cristina, Vang, Jan
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