Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Emerging technologies as the next pandemic?: Possible consequences of the Covid crisis for the future of responsible research and innovation. [PDF]
Stahl BC.
europepmc +1 more source
Knowledge, Spillovers and Firms’ International Growth. An Analysis at the Italian NUTS 3 Level [PDF]
In the framework of analyses on the relationship between geography and technological innovation, the role of universities has received considerable attention.
Andrea Bonaccorsi +2 more
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Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan +14 more
wiley +1 more source
Cities around the world are using smart city approaches to transform urban infrastructures toward sustainability. Critical academic studies of smart city projects often fail to integrate the aspect of care.
Benedict Lang
doaj +1 more source
Responsible Research and Innovation Framework, the Nagoya Protocol and Other European Blue Biotechnology Strategies and Regulations: Gaps Analysis and Recommendations for Increased Knowledge in the Marine Biotechnology Community. [PDF]
Schneider XT +6 more
europepmc +1 more source
Regional specialised observatories networks in technological development and innovation exemplified by the Silesia Voivodship [PDF]
The Regional Specialised Observatories Network is a systemic tool to encourage interdisciplinary cooperation between the key participants of the regional innovation system in order to build the competitive advantage of the region. The network responds
Bondaruk, Jan +4 more
core
Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig +9 more
wiley +1 more source
Effective inter-organisational networks for Responsible Research and Innovation and global sustainability: a scoping review. [PDF]
Farrugia DM, Vilches SL, Gerber A.
europepmc +1 more source
Responsible Innovation for Decent Nonliberal Peoples: A Dilemma? [PDF]
It is hard to disagree with the idea of responsible innovation (henceforth, RI), as it enables policy-makers, scientists, technology developers, and the public to better understand and respond to the social, ethical, and policy challenges raised by new ...
Wong, Pak-Hang
core

