Results 111 to 120 of about 1,354,140 (303)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Addressing responsible research and innovation to industry [PDF]

ACM SIGCAS Computers and Society, 2016
Responsible research and innovation (RRI) is taking a role to assist all types of stakeholders including industry to move research and innovation initiatives to responsible manner for tackling grand challenges. The literature on RRI focuses little on how industry can implement RRI principles.
openaire   +2 more sources

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Operationalising Responsible Research and Innovation – tools for enterprises

Engineering Management in Production and Services, 2019
Responsible Research and Innovation (RRI) is an emerging paradigm and a novel approach to governing science and innovation with the aim of making them ethically acceptable and socially desirable.
Nazarko Lukasz, Melnikas Borisas
doaj   +1 more source

The medium-term sustainability of organisational innovations in the national health service [PDF]

, 2011
Background: There is a growing recognition of the importance of introducing new ways of working into the UK's National Health Service (NHS) and other health systems, in order to ensure that patient care is provided as effectively and efficiently as ...
A Neath, A Pettigrew, BM Sibthorpe, C May, C Pollitt, D Buchanan, DA Buchanan, E Ferlie, E Rogers, G Currie, G Martin, GP Martin, GP Martin, GP Martin, GP Martin, Graeme Currie, Graham P Martin, J Jones, J Ritchie, JL Denis, KM Eisenhardt, L Fitzgerald, L Fitzgerald, NHS Institute, P Bate, Rachael Finn, RK Yin, Ruth McDonald, S Dopson, T Greenhalgh, T Reay, TB Lawrence   +31 more
core   +3 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Responsible Research and Innovation in Science Education: the IRRESISTIBLE Project [PDF]

, 2015
The EU funded IRRESISTIBLE-project (Project Coordinator: Jan Apotheker, University of Groningen, Netherlands) develop activities designed to foster the involvement of high school and elementary students and the public in Responsible Research and ...
Apotheker, J., Bertozzi, E, FAZIO, Claudio, FLORIANO, Michele, Levrini, O, MANIACI, Roberta, Pecori, B, Venturi, M   +7 more
core  

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Contextualizing Security Innovation: Responsible Research and Innovation at the Smart Border? [PDF]

Sci Eng Ethics, 2021
Klimburg-Witjes N, Huettenrauch FC.
europepmc   +1 more source

Responsible Research and Innovation in Construction

Procedia Engineering, 2016
Abstract The issue of ethics and responsibility is gaining attention among the creators of scientific policy, funding agencies and society at large. Responsible research is defined as research that aligns both the process and the outcomes with the values, needs and expectations of society.
openaire   +1 more source